Endocrine Abstracts

Introduction: Thyrotropin (TSH)-secreting pituitary adenomas are rare (<1% of all pituitary tumors) and cause secondary hyperthyroidism.Case report: A 33-year old woman with type 1 diabetes mellitus presented in 2009 with palpitations. She had a past medical history of radioiodine therapy for thyrotoxicosis in 1998. After radioiodine treatment, she received an increasing daily dose of thyroxine (from 50 to 175 μg) because of her gradually rising...

Endostatin, a cleaved fragment of collagen XVIII, is a potent endogenous angiogenesis inhibitor. Elevated serum endostatin levels have been recently reported in patients with various types of neoplasms. The purpose of our study was to evaluate serum concentrations of endostatin in patients harbouring various types of pituitary adenomas and to examine the relationship of serum endostatin levels to circulating vascular endothelial growth factor (VEGF) levels. Preoperative serum ...

Introduction: Pheochromocytomas are rare neuroendocrine tumors arising from chromaffin cells of the adrenal medulla. Approximately 10% of all pheochromocytomas are malignant. There is no effective therapy for malignant pheochromocytoma (MAL-PHEO) and the overall prognosis is poor.Case report: We report 22-year survival with MAL-PHEO in a patient treated with several surgeries, 131I-metaiodobenzylguanidine and, subsequently, with long-acting fo...