Endocrine Abstracts

‘Silent’ ACTH-secreting pituitary adenomas are not characterized by specific clinical features that would suggest the presence of hypercortisolism. In contrast, they present as non-functioning pituitary macroadenomas with either visual compromise or hypercortisolism. However, immunostaining reveals ACTH-secreting cells.In order to characterize the laboratory features of these tumours, we have preoperatively assessed 56 patients with either clin...

Objectives: DOTAMZOL is a DOTA-conjugated bisphosphonate which can be used for diagnostic (44Sc, 68Ga) or therapeutic (177Lu) applications. The aim of this study was to evaluate the adaption of the radiolabelling process on an automated module utilizing NaCl-post processing, with regard to clinical application and additional radiation protection point of view.Methods: 68Ga was obtained from a 1.5 yea...

Objective: The performance of two functional bioassays and two immunoassays for the measurement of TSHR-Ab was assessed in this multicenter study.Methods: Two-hundred two subjects (median age 54 years, 162 female, 80%), with well-documented thyroid disorders and controls were prospectively enrolled in a consecutive, unselected manner. Antibody measurements were performed in a blinded manner using the Bridge (Siemens, performed at the Dartmouth-Hitchcock ...