Searchable abstracts of presentations at key conferences in endocrinology

ea0031cmw4.3 | Managing Hypoglycaemia | SFEBES2013

Hypoglycaemia in neonates and Children

Hussain Khalid

Hypoglycaemia is one of the most common biochemical abnormalities observed in the neonatal, infancy and childhood periods. Despite the commonality there is still confusion about the definition and management of hypoglycaemia. Hypoglycaemia can be due to many causes (including endocrine and metabolic) in the neonatal, infancy and childhood period. For example hyperinsulinaemic hypoglycaemia is the most severe form of hypoglycaemia in the neonatal period whereas ‘ketotic&#1...

ea0027s7 | CME Session | BSPED2011

Hyperinsulinaemic hypoglycaemia

Hussain Khalid

Hyperinsulinaemic hypoglycaemia (HH) is a cause of severe and persistent hypoglycaemia in the newborn period. It is an extremely heterogeneous disorder with respect to clinical presentation, pancreatic histology and molecular biology. The clinical severity of HH varies mainly with age at onset of hypoglycemia (severe hypoglycemia in neonates) and has major consequences in terms of therapeutic outcome and genetic counseling. The commonest genetic cause of persistent HH are auto...

ea0016s6.3 | Insights in pancreatic development and new clinical aspects | ECE2008

Hyperinsulinism in humans

Hussain Khalid

Hyperinsulinism causes recurrent and severe hypoglycaemia in the newborn, infancy and childhood period. Although the condition is more common in the newborn period it can present even adults can present with late onset hyperinsulinaemic hypoglycaemia not due to an insulinoma (noninsulinoma pancreatogenous hypoglycemia). Hyperinsulinaemic hypoglycaemia encompasses a heterogeneous group of disorders with respect to clinical presentation, pancreatic histology and molecular biolog...

ea0039ep57 | Diabetes | BSPED2015

Impact of best practice tariff (BPT) for accessing psychological service by diabetic children and young people

Alsaffar Hussain , Satish Hulikere

Introduction: 25 314 children and young people <18 years with diabetes in England and Wales have been looked after in 178 paediatric diabetic units (PDUs) across the country. In 2012–2013, BPT has been introduced with 13 mandatory requested criteria, one of them is; each patient should have an annual assessment as to whether input to their care by a clinical psychology input is needed, and access to psychological support as appropriate. Therefore we aimed to study the...

ea0060p29 | (1) | UKINETS2018

The role of imaging in neuroendocrine tumours

Hussain Tahir , Ganatra Rakesh

The imaging of neuroendocrine tumours (NET) is multimodal and is often initiated by cross sectional imaging, usually CT. Imaging with CT demonstrates metastatic disease more frequently than locating the primary lesion. Subsequent imaging relies on somatostatin receptor (SSR) scintigraphy, usually with the use of indium octreotide. SSR scintigraphy is commonly supplemented with SPECT CT to help localise the sites of metastatic deposits more accurately by delineating the associa...

ea0033p36 | (1) | BSPED2013

Insulin pumps for adolescents and young people; main problems observed in Macclesfield: United Kingdom

Alsaffar Hussain , Chandrasekaran Surendran

Introduction: Continuous s.c. insulin infusion delivered via insulin pump has enabled patients with diabetes mellitus type 1 to improve metabolic control and lead healthier lives1. However some patients are experiencing problems with their pumps.Aim and methods: A service review was carried out to look at the incidence of pump related problems using an online questionnaire survey.Results: The response rate was 85% for th...

ea0033p37 | (1) | BSPED2013

Insulin pumps for adolescents and young people improve their quality of life

Alsaffar Hussain , Chandrasekaran Surendran

Introduction: The study aimed to review the service provided for children and young people with type 1 diabetes mellitus focusing on their quality of life (QoL) before and after commencing insulin pump therapy.Methods: An online survey using survey monkey was carried out. Each questionnaire had 10 questions and it was filled by either patients or their parents based on the age group.Results: Forty-two patients are currently on insu...

ea0055wa3 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Lymphocytic hypophysitis in a pregnant patient with type 1 diabetes

Hussain Shazia , Shahriar Huda Mohammed , Drake William

A 34-year old female with type 1 diabetes presented to the antenatal clinic complaining of polydipsia, polyuria and nocturia. She was 12 weeks pregnant with adequate glycaemic control on a basal-bolus insulin regime. She reported new onset headaches but no deterioration in vision. On examination, her visual fields were full to confrontation with red pin. She was eunatraemic (Na 138 mmol/l), had an early morning cortisol of 332 nmol/l and normal thyroid function tests (FT4 16 p...

ea0055wf3 | Workshop F: Disorders of the gonads | SFEEU2018

Honesty is always best

Hussain Shazia , Storr Helen , Drake William

A three year old boy was referred for surgical correction of an undescended right testis. Intra-operatively he was found to have a hyperplastic right gonad which was in continuation with a unilateral fallopian tube, prompting analysis of his karyotype. This showed 46XX/XY mosaicism with 88% of the cells being XX and 12% XY. The post-operative histology confirmed mixed testicular and ovarian tissue in the right gonad. He appeared phenotypically male and had blaschko lines consi...

ea0055cb15 | Additional Cases | SFEEU2018

A rare cause of elevated testosterone levels in an adult female

Hussain Shazia , Sahdev Anju , Drake William

A 49 year old Russian lady was found to have an elevated testosterone level (9 nmol/l) when investigated for hair loss. This was first detected some years ago when she apparently was given a provisional diagnosis of polycystic ovarian syndrome. When assessed in her local endocrine unit she did not report any excessive body hair growth or symptoms of virilisation. She claimed to reach the menopause aged 45 years and reported a family history of early menopause. Initial blood te...