Searchable abstracts of presentations at key conferences in endocrinology

ea0055wa5 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Selective-Serotonin-Re-uptake inhibitor induced SIADH on a background of post-operative Diabetes Insipidus

Ilangaratne Charmaine , Anandappa Samantha , Ogunko Arthur , Mohandas Cynthia , Abedo Itopa

We present a case of a 79 year old gentleman who attended the emergency department with a one day history of acute confusion and hallucinations. His background included trans-sphenoidal surgery for a gonadotrophic pituitary macro-adenoma in 2012 with subsequent panhypopituitarism and post-operative diabetes insipidus. He also had a history of restless-leg-syndrome for which he took Amitriptyline chronically, COPD and tablet-controlled diabetes mellitus. Of significant note, th...

ea0055we4 | Workshop E: Disorders of the adrenal gland | SFEEU2018

Challenging diagnosis of phaeochromocytoma

Anandappa Samantha , Ilangaratne Charmaine , Abedo Itopa , Ogunko Arthur , Mohandas Cynthia

A 64 year old female with a background history of hypertension resistant to dual therapy had recurrent admissions to the local emergency department with pulmonary oedema and chest tightness over the preceding 3 months associated with fluctuations in Troponin I levels. This led to multiple cardiac investigations including invasive coronary angiogram which did not report any abnormality. Her blood pressure was elevated at 200/120 mmHg and an electrocardiogram demonstrated sinus ...

ea0055wa4 | Workshop A: Disorders of the hypothalamus and pituitary (I) | SFEEU2018

Extreme polydipsia as an emergency presentation of chronic undiagnosed central diabetes insipidus

Anandappa Samantha , Youn Suhyun , Anpalakhan Sheela , Ilangaratne Charmaine , Mohandas Cynthia , Abedo Itopa , Ogunko Arthur

Isolated Central Diabetes Insipidus is a rare condition characterised by deficiency of arginine vasopressin (AVP) which presents with polyuria and polydipsia. The reported prevalence of diabetes insipidus is 1 in 25,000. The pathogenesis of central diabetes insipidus is often uncertain however the known causes can be divided into acquired, through trauma or vascular injury as well as infiltrative including malignancy, and congenital abnormalities which accounts for less than 1...

ea0024oc2.3 | Oral Communications 2 (Brief Communications) | BSPED2010

The phenotype of late-presenting congenital hyperinsulinism

Ilangaratne C , Rigby L , Skae M , Flanagan S , Ellard S , Banerjee I , Clayton P , Members NORCHI

Background: Children with hypoglycaemia due to Congenital Hyperinsulinism (CHI) usually present in the neonatal period but late presentations also occur. The phenotype of late-presenting CHI has not been well described.Aim and methods: We have reviewed the clinical course of children (n=22) presenting with CHI after 1 month of age in relation to mode of presentation, rapid KATP genetic mutation analysis, neurodevelopment, clinical progr...