Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep409 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Improving safety in diabetes management and reducing insulin errors in hospital – practically achievable or a utopian fantasy?

Burbridge Wyn , Braycotton Lynne , Puttanna Amar , Yadagiri Mahender , Ilsley Dee , Mukhopadhyay Sagnik , Munichoodappa Karthik , De Parijat

42 insulin related incidents were reported within our Trust in 2014. Subsequent Root Cause Analysis revealed numerous insulin errors, hyperglycemia mismanagement and highlighted significant deficits in diabetes knowledge amongst nursing staff. To address the above issues, new safety interventions were introduced and five key outcomes are:1. A new stand-alone insulin prescription chart introduced May’15 has seen insulin incidents dec...

ea0024p37 | (1) | BSPED2010

Type 2 diabetes in childhood: building a platform for interventions to prevent the progression to cardiovascular disease

Barnett A , Barrett T , Cotter C , Dunger D , Fulton E , Heywood J , Ilsley E , O'Brien A , Shield J , Wales J

Type 2 diabetes (T2DM) is increasing in children in the UK and worldwide, most likely related to the rising prevalence of obesity. We are developing a UK national cohort of children (under 18 completed years) with diabetes defined by WHO criteria, suspected type 2, BMI above 85th centile; but who do not have genetically confirmed monogenic diabetes, secondary diabetes, or any evidence of pancreatic autoimmunity. The aim of this study is to describe the characteristics of the f...

ea0033oc3.2 | Oral Communications 3 | BSPED2013

GAD and IA2 autoantibody positivity is associated with a requirement for insulin treatment: results of the UK national paediatric Type 2 Diabetes cohort

Gray Zoe , Ilsley Emma , Cotter Catherine , Makusha Lydiah , Ford Anna , Turner Kelly , Heywood James , Chandler Kyla , Bingley Polly , Barnett Anthony , Dunger David , Shield Julian , Wales Jeremy , Barrett Timothy

Objectives: To establish the frequency of islet cell autoimmunity in children with a clinical diagnosis of type 2 diabetes (T2DM) and describe associated clinical and laboratory findings.Methods: We recruited children with: paediatrician diagnosis of T2DM; BMI above 85th centile for age and sex; children with other confirmed diagnoses such as monogenic and type 1 diabetes (T1DM) were excluded. Clinical data was collected into a national database. Blood w...

ea0030oc4.3 | Oral Communications 4 | BSPED2012

White UK children are older, more obese and more insulin resistant than non-White UK children at diagnosis of type 2 diabetes: baseline results of the UK national type 2 diabetes cohort

Gray Zoe , Ilsley Emma , Cotter Catherine , Makusha Lydiah , Ford Anna , Turner Kelly , Heywood James , Barnett Anthony , Dunger David , Hamilton-Shield Julian , Wales Jeremy , Barrett Timothy

Objectives: Type 2 diabetes (T2DM) has increased in UK children since the first reports in 2000; however it is poorly characterised and management practice varies across the UK. We aimed to describe the characteristics of the first 125 children recruited to the UK national study.Methods: We recruited children with: paediatrician diagnosis of T2DM; body mass index (BMI) above 85th centile for age and sex; other diagnoses such as monogenic diabetes exclude...

ea0027oc4.2 | Oral Communications 4 | BSPED2011

White UK children are older, more obese and more insulin resistant than non-White UK children at diagnosis of type 2 diabetes: baseline results of the UK national type 2 diabetes cohort

Barrett Timothy , Gray Zoe , Ilsley Emma , Cotter Catherine , Ford Anna , Turner Kelly , Heywood James , Barnett Anthony , Dunger David , Hamilton-Shield Julian , Wales Jeremy

Type 2 diabetes (T2DM) has increased in UK children since the first reports in 2000; however it is poorly characterised and management practice varies across the UK. We aimed to describe the characteristics of the first 103 children recruited to a national study. We wrote to paediatricians asking for children with: diagnosis of T2DM; body mass index (BMI) above 85th centile for age and sex; and other diagnoses such as monogenic diabetes excluded. Clinical data was collected in...

ea0033p30 | (1) | BSPED2013

GAD and IA2 autoantibody positivity is associated with a requirement for insulin treatment: results of the UK national paediatric type 2 diabetes cohort

Gray Zoe , Ilsley Emma , Cotter Catherine , Makusha Lydiah , Ford Anna , Turner Kelly , Heywood James , Chandler Kyla , Bingley Polly , Barnett Anthony , Dunger David , Hamilton-Shield Julian , Wales Jeremy , Barrett Timothy

Objectives: To establish the frequency of islet cell autoimmunity in children with a clinical diagnosis of type 2 diabetes (T2DM) and describe associated clinical and laboratory findings.Methods: We recruited children with paediatrician diagnosis of T2DM and body mass index (BMI) above 85th centile for age and sex. Patients with other confirmed diagnoses such as monogenic and type 1 diabetes (T1DM) were excluded. Clinical data was collected into a nation...