Searchable abstracts of presentations at key conferences in endocrinology

ea0011p472 | Endocrine tumours and neoplasia | ECE2006

Stimulated and spontaneous growth hormone release in irradiated acromegalic patients

van der Klaauw AA , Pereira AM , van Thiel SW , Smit JWA , Corssmit EPM , Biermasz NR , Frohlich M , Iranmanesh A , Veldhuis JD , Roelfsema F , Romijn JA

Growth hormone deficiency frequently occurs as consequence of radiation therapy in pituitary disorders. However, it not known whether radiation therapy in acromegaly results in comparable diminution of GH secretion. We therefore hypothesized that stimulated and spontaneous GH release is ultimately indistinguishable in irradiated acromegalic patients and irradiated patients with other pituitary disorders. For this study 10 acromegalic patients and 10 patients with other pituita...