Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep935 | Reproductive and Developmental Endocrinology | ECE2022

Hormonal changes in women with abnormal endometrial bleeding in peri and postmenopause

Kocevska Ana , Ismaili Bashkim , Skeparovska Kristina , Georgiev Dimitar , Spisic Ana Marija , Izairi Pranvera

Objectives: To determine the histopathological changes of the endometrium that occur during the period of perimenopause and postmenopause and to determine their association with the presence of obesity, diabetes, thyroid disorders and the levels of FSH, LH, estradiol, insulin and parathormone.Material and methods: This study involved 120 patients with fractionated explorative curettage due to abnormal uterine bleeding. The control group consisted of 40 h...

ea0037ep474 | Diabetes (complications & therapy) | ECE2015

Prevalence of microalbuminuria and predictive factors in a group of Albanian diabetic adults

Spahiu Eduard , Ismaili Mimoza , Shehu Aldi , Thengjilli Erion , Doko Albana , Toti Florian

Background and aims: Diabetic nephropathy is one of the most prevalent and dangerous chronic complication of diabetes mellitus. Its end-stage, renal chronic failure is the most important cause of premature death in diabetic patients. Microalbuminuria (MA), one of the first signs of diabetic nephropathy, may be present from the moment of diagnosis in type 2 diabetes. The aim of our study was to determine the prevalence of microalbuminuria and to identify predictor factors in a ...

ea0081ep906 | Reproductive and Developmental Endocrinology | ECE2022

Primary Ovarian Insufficiency in RMND1 Mitochondrial Disease

Boros Emese , Elilie Mawa Ongoth Farel , Heinrichs Claudine , Mansbach Anne Laure , Seneca Sara , Aeby Alec , Ismaili Khalid , Brachet Cecile

Context: The genes implicated in premature ovarian failure play a role in crucial biologic processes such as DNA repair, meiosis, germ cell recruitment, steroidogenesis and mitochondrial function. Mitochondrial disorders are varied in their onset, inheritance pattern, and clinical presentation, but they often cause dysfunction in organs with high energy demands. Frequent features include hypertrophic cardiomyopathy, heart conduction defects, myopathy, sensorineural deafness, c...

ea0006p35 | Endocrine tumours and neoplasia | SFE2003

THE SENSITIVITY OF (super)123I-MIBG IN THE DETECTION OF HISTOLOGICALLY CONFIRMED CATECHOLAMINE-PRODUCING TUMOURS

Ismail M , Foley R , Drake W , Grossman A , Jenkins P , Chew S , Besser G , Resnek R , Britton K , Monson J

THE SENSITIVITY OF 123I-MIBG IN THE DETECTION OF HISTOLOGICALLY CONFIRMED CATECHOLAMINE-PRODUCING TUMOURS.M Ismail, R Foley, WM Drake, AB Grossman, PJ Jenkins, SL Chew, GMBesser, R Reznek, K Britton, JP MonsonDepartments of Endocrinology, Nuclear Medicine and Radiology, StBartholomew's Hospital (QMUL), London EC1A 7BERadionuclide imaging is widely used for the loc...

ea0090p770 | Thyroid | ECE2023

Does targeting a TSH ≤ 2.5 mmol/l improve fertility in euthyroid women?

Nasri Ismail

Introduction: hypothyroidism is among the most frequent causes of infertility, our objective is to analyze this population in order to evaluate the effectiveness of treatment with levothyroxine.Patients and methods: this is a retrospective interventional study from September 2017 to September 2022.Inclusion criteria: infertility, TSH>2.5 mmol/lExclusion criteria: infertility for less than 1 year, age ≥ ...

ea0090ep526 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

GAZA study (Glycémie Améliorée Zéro Antidiabétique), a new antidiabetic therapeutic approach without pharmacoligical treatment

Nasri Ismail

Introduction: In diabetology all the recommendations insist on the intensification of the antidiabetic treatment with the maintenance of the same treatment if the type 2 diabetes mellitus is balanced. Our work insists on dietary treatment and focuses on weight loss in order to degress antidiabetic treatment until cessation.Patients and methods: This is a prospective interventional study. Type 2 diabetes mellitus on pharmacological treatment: treatment is...

ea0090ep527 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Diabetes and Ramadan, special Ramadan blood glucose self-monitoring table

Nasri Ismail

Background: International Diabetes Federation (IDF), in collaboration with the Diabetes and Ramadan (DAR) International Alliance proposed in 2021, IDF-DAR Practical Guidelines with a score that allows certain patients even on insulin to fast which requires regular and appropriate blood glucose monitoring.Aim: Develop a special Ramadan blood glucose self-monitoring table in order to limit the risk of acute compilations during this month.<p class="abst...

ea0063p137 | Diabetes, Obesity and Metabolism 1 | ECE2019

The EMPA-REG OUTCOME, a real cardiovascular benefit or a play on words?

Nasri Ismail

Introduction: The EMPA-REG OUTCOME is a cardiovascular safety study with empaglifozin that has shown a reduction in cardiovascular mortality and a decrease in hospitalization for heart failure. Our work is based on the analysis of the protocol that recognized five changes, the last, 3 years after the start of the study and which affects the definitions of the elements of the primary composite, and following these modifications, we find that the mortality Cardiovascular was inc...

ea0038se1.5 | (1) | SFEBES2015

Understanding the biochemistry underpinning hypoglycaemia of the insulin autoimmune syndrome (IAS) is paramount for diagnosis and management

Ismail Adel

IAS is common in Japanese but rare in Caucasians. Highlighting its aetiology is paramount in understanding its clinical and analytical variabilities and can help planning investigations and avoid mistakes in the interpretation of false pancreatic endocrine data commonly associated with this syndrome.The underlying aetiology of IAS is the presence of high affinity/avidity endogenous insulin autoantibodies in significant amounts in non-diabetics. Clinicall...

ea0086p147 | Thyroid | SFEBES2022

An Unusual Presentation of An Autoimmune thyroid Disease

Alkaabi Fatima , Ismail Mohammed

40years old lady with 12 months history of hyperthyroidism. Treated with ATD. Referred by her treating physician for RAI therapy due to intolerance to ATD and high dose requirement after 12 months. Patient being treated as Classical Graves’ Hyperthyroidism. She had symptoms of hyperthyroidism at time of presentation but none at time of assessment in our hospital. Main current issue was painful neck swelling: developed slowly over preceding two months. No problems with swa...