Endocrine Abstracts

Objective: The present study designed to assess the effect of Mg+Zn, vitamin C+E, and combination of these micronutrients on blood pressure in type 2 diabetic patients.Materials and methods: In a randomized, double-blind, placebo controlled clinical trial, 69 type 2 diabetic patients were randomly divided into four groups, each group receiving one of the following daily supplement for 3 months; group M: 200 mg and 30 mg Zn (n=16), group V: 200 mg...

Polycystic ovary syndrome is a common endocrine disorder in women was associated with lipid disorders with increased risk of cardiovascular disease and obesity are associated. This study aimed to compare the lipid profile and fasting plasma glucose levels, insulin resistance in women with polycystic ovary syndrome is done with the control group.Methods: This case–control study on 153 women with PCOS and 449 healthy control subjects from 4 cities in ...

Excitatory amino acid neurotransmitters (EAA) play an essential role in regulation of GH secretion in the central nervous system. Involvement of EAA path way in the secretion of GH was indicated by early finding that NMA stimulate GH secretion via direct release of hypothalamic GHRH. The present study was designed to investigate the involvement of excitatory amino acid neurotransmitter’s (EAA) pathway in the regulation of basal as well as stimulated GH secretion in primat...

Hypoglycemia result in significant activation of various neuroendocrine pathways involved in producing peripheral hormonal and metabolic responses aimed at restoring euglycemia. The present study was designed to investigate the involvement of excitatory amino acid neurotransmitter’s (EAA) pathway in the regulation of basal as well as physiologically stimulated PRL secretion in primates. Four adult male Rhesus monkeys (Macaca mulata) were used in the study. Four set...

The endogenous opiates cause a rapid increase in PRL secretion. The present study was designed to investigate the involvement of opioidergic pathway in the regulation of PRL secretion by the endogenous excitatory neurotransmitters in primates. In the first set of experiments saline infusion (3 ml/h) for a period of 3 h was given. In the second set of experiment NMA injections were administered with one hr interval. In the third set of experiment NAL infusion (5 mg/3 ml per h) ...

Introduction: The aim of the study was to asses frequency of the components of metabolic syndrome (MS) according to the criteria of the International Diabetes Federation (IDF) in patients with adrenal incidentaloma (AI) without hormonal activity.Design: The study comprised of patients with AI without hormonal activity, confirmed in CT. The adrenal function was determined by measuring circadian rhythm of cortisol and/or dexametasone suppression test, aldo...

Introduction: The aim of the study was to examine the risk factors associated with diabetic retinopathy (DR) in adult patients with DM1 and DM2.Design: The study group consisted of adults patients with DM1 and DM2, diagnosed according to the WHO criteria. Risk factors for diabetic retinopathy were evaluated on the demographic data, medical history, clinical and biochemical parameters related to metabolic control of diabetes. We collected also ophthalmic ...

Introduction: This study aimed to investigate possible direct and indirect association of socio-demographic and lifestyle factors with central obesity and overweight status in the Tehran Lipid and Glucose Study (TLGS) population.Methods: After excluding under- and over-reporters, a sample of 2747 TLGS participants (58.3% female) aged≥20 years were recruited in the study. Overweight and central obesity were defined as having BMI ≥25 kg/m2...

Introduction: To assess the effect of community-based multidisciplinary lifestyle interventions on metabolic syndrome (MetS) and its components in an urban population of Iranian adolescents.Methods: This longitudinal study was conducted on 1230 adolescents, aged 12–15 years, within the framework of the TLGS. They were categorised in three groups: those residing in the intervention area during study (complete intervention group; n=195); thos...