Abstract Search

ea0028p304 | Steroids | SFEBES2012

HSD11B1 promoter binding of the NF-κB p65 subunit in response to TNF-α suppresses 11β-HSD1 expression and activity in C2C12 muscle cells

Doig Craig , Bashir Jamila , Zielinska Agnieszka , Cooper Mark , Stewart Paul , Lavery Gareth

A counter-regulatory rise in GC levels is important to the inflammatory response, that when impaired is associated with high mortality in inflammatory states. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates intracellular glucocorticoids (GC), amplifying their actions, and has been postulated to play a role in the development of inflammation-associated arthritis, obesity and myopathy. Pro-inflammatory cytokines (e.g. TNF-α) increase expressio...

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ea0030p42 | (1) | BSPED2012

Feasibility of measuring birth length and parental height for small babies and following-up short children at 2 years

Sardar Colette Montgomery , Kinmond Sheena , Siddique Jamila , McGowan Sheena , Paterson Wendy , Donnelly Sharon , Gault Emma Jane , Donaldson Malcolm

Background: Small for gestational age (SGA) and short stature at birth can be defined as birth weight (BW) and birth length (BL) ≤−2 S.D.. Affected neonates can be classified as: i) SGA, ii) Short, iii) SGA + Short. Catch-up growth occurs by age 6 months in 9095% of Short and SGA + Short infants. A minority remain short after age 24 years when the lack of data on BL and parental height (PH) renders assessment difficult.<p class="abste...

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Endocrine Abstracts

HSD11B1 promoter binding of the NF-κB p65 subunit in response to TNF-α suppresses 11β-HSD1 expression and activity in C2C12 muscle cells

Feasibility of measuring birth length and parental height for small babies and following-up short children at 2 years

BiosciAbstracts