ea0011p846 | Thyroid | ECE2006
Bullock M
, Jehani M
, Bowden P
, Ludgate M
Patients with non-functional FOXE1 (forkhead transcription factor) display congenital hypothyroidism, spikey hair and other abnormalities. In the thyroid, FoxE1 controls migration of the developing gland and adult expression of thyroid specific genes. Our earlier studies demonstrated FOXE1 protein expression in keratinocytes of the epidermis and hair-follicle outer root sheath.We aimed to characterise the expression and functional activity of...