Endocrine Abstracts

Introduction: Charcot foot is a painless progressive osteoarthropathy of one or more joints due to an underlying neurological lesion, leading to deformities of the foot by the non-infectious destruction of bones and joints.The interest of this observation is to show on the one hand the role that the education of diabetics plays in the early diagnosis of Charcot foot and on the other hand the need for a multidisciplinary team in the care of the foot of Ch...

Introduction: Growth retardation in sickle cell children is common and multifactorial. Recent evidence suggests damage to the somatotropic axis. We report the case of a patient followed for homozygous sickle cell anemia and in whom we discover an associated GH deficiency.Observation: It is a 13 year old child followed for homozygous sickle cell anemia, splenectomized for 2 years, not polytransfused. We were sent to the hematology department before a dela...

Background: Pituitary gland metastasis is rarely the initial presentation of metastatic cancer. Most cases of pituitary gland metastasis are asymptomatic with diabetes insipidus being the most common symptomatic presentation. It can rarely present with symptoms of hormone underproduction such as anterior pituitary deficiency. Although pituitary gland metastasis is rare, it is underestimated, as it is commonly misdiagnosed with pituitary gland adenoma due to the lack of clear r...

Sexual differentiation is a sequential process where several genes are involved, therefore a defect at any stage can lead to a divergence between genetic, gonadal and phenotypic sex. The objective of our work is to analyze the clinical and hormonal characteristics of 13 XY patients, explored between 1989 and 2007 and belonging to 10 different families. The average age of our patients was 18.9 years (2–33 years). The reason for consultation was sexual ambiguity in two case...

Introduction: 11-Hydroxylase deficiency is a rare form of congenital adrenal hyperplasia characterized by glucocorticoid deficiency, hypertension, hypokalemia and virilization in females. We report a case of congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency revealed by bilateral papilledema in the context of arterial hypertension.Case report: A 13-year-old patient, with no medical history, presented with complains of headache, vomiting ...

Introduction: COVID-19 is a novel pandemic affecting globally. It has led to an unprecedented global health crisis assessing health system’s preparedness to deal with health disasters. The aim of our study was to evaluate the impact of COVID-19 on the follow up care of diabetic patients.Methods: We conducted a retrospective study in 100 insulin-requiring diabetic patients. Data regarding treatment availability, weigh, glycemic control and follow up ...

Introduction: In Tunisia, the prescription of insulin analogs is increasingly « automatic » by practicians, convinced by this treatment superiority over human insulin in diabetes management. The aim of our study is to determine whether the analogs prescription modalities and advantages are known by the patients, and to assess the factors associated with this knowledge.Patient and Methods: We conducted a retrospective study including 65 diabetic...

Introduction: Choroidal metastases are among the most common malignant ocular tumors. In the majority of cases, their origin is pulmonary in men and mammary in women. We present a rare case of choroidal metastasis from a vesicular thyroid carcinoma.Case presentation: A 35-year-old woman presented to our department complaining of progressive vision reduction in the right eye. Six years previously, she was operated for vesicular carcinoma of the thyroid wi...

Introduction: Neurofibromatosis type 2 (NF2) is an autosomal dominant genetic disorder that cause a growth of noncancerous tumors in the nervous system, it associates cranial schwannomas, meningiomas, and skin and ophthalmologic lesions. It is a rare condition and its association with an intrasellar arachnoidocele has not been reported yet. We report the case of a patient who presents a NF2 associated with hypopituitarism related to an intrasellar arachnoidocele.<p class="...

Introduction: Graves’ ophthalmopathy, also called Graves’ orbitopathy, is a potentially sight-threatening ocular disease that has puzzled physicians and scientists for nearly two centuries. Generally occurring in patients with hyperthyroidism or a history of hyperthyroidism due to Graves’ disease, Graves’ ophthalmopathy is also known as thyroid-associated ophthalmopathy or thyroid eye disease, because it sometimes occurs in patients with euthyroid or hypoth...