Endocrine Abstracts

Introduction: Dual nivolumab and ipilimumab immunotherapy has the potential of causing an immune-mediated thyrotoxicosis, precipitating thyroid storm.Case details: A 62-year-old Caucasian woman with a history of Lung Carcinoma (Non small Cell Lung Carcinoma) presented to the emergency department, with a 3-day history of intractable nausea, severe headache, vomiting and anxiety.She had been initiated on dual nivolumab and ipilimumab...

Introduction: Psychogenic polydipsia is a relatively uncommon condition characterized by overconsumption of water. It is known to be prevalent amongst psychiatric patients, but less common in the general population.Case report: A previously well 18-month-old girl presented to the emergency department in status epilepticus. There was no history of fever, recent weight loss, infection, trauma or any systemic medications. Post event questioning established ...

Case History: We report the case of a 25-year-old Asian male who presented to our hospital with recurrent episodes of abdominal pain complicated by significant Hyponatremia. Initial admission was in November 2021 followed by March, 2022 with similar symptoms. He remained under surgical care during both admissions. For his severe hyponatremia, an urgent Endocrine input was sought. The patient was not on any medications that could be implicated in his biochemical picture and his...

Introduction: Regional Migratory Osteoporosis (RMO) is a rare condition, characterised by a self-limiting migratory arthralgia, which generally tends to involve the lower limbs. The arthralgia is usually, not associated with any history of trauma. Radiologically, Magnetic Resonance Imaging (MRI) is the investigation of choice. Bone Marrow Oedema (BMO) with subchondral sparing are the usual findings in patients with RMO. This condition is usually under diagnosed due to the comp...

Introduction: Lymphocytic Hypophysitis (LH) is an autoimmune endocrinopathy characterised by extensive infiltration of the anterior pituitary gland with chronic inflammatory cells, thus causing pituitary expansion and a variable degree of hypopituitarism closely mimicking the features noted in pituitary adenoma and seen most frequently in women. The aetiology has a general preponderance of occurring at the end of gestation or during the early postpartum period.<p class="ab...

Introduction: Primary hyperparathyroidism (P-HPT) is a common endocrine disorder that occurs as result of adenomas (80–85%), hyperplasia (10–15%), atypical adenoma or carcinomas (<1%). Atypical parathyroid adenoma (APA) is a rare entity and represents intermediate group of parathyroid neoplasms of uncertain malignant potential with some atypical histological features.Case details: We report a case of a 34-year male, with a background of h...

A previously well 55 year old man presented to his family practitioner with asix week history of dyspepsia. He denied any other symptoms including no weight loss. Clinical examination was normal.A gastroscopy was organised which revealed a 10 millimetre sessile polyp located at greater curvature at the lower body of the stomach. The polyp was removed by snaring. Histological examination of the polyp revealed heterotopic pancreatic ...

A 55 year old lady was referred by her general practioner with a six months history of generalised lethargy and cold intolerance.This was associated with abdominal bloating and constipation.She had been more irritable recently and was getting depressed. She also described symptoms suggestive of carpal tunnel syndrome. The only past history of note was of lactose intolerance.There was no family history of thyroid disorder.On examination she was clinically...

IntroductionHyperprolactinemia is a condition in which a person has higher-than-normal levels of the hormone prolactin in the blood. It is a relatively common condition encountered in the world of endocrinology. It is often seen as a side-effect with usage of anti-psychotics. Treatment options when symptomatic usually constitute dopamine agonist therapy, the common agents being Cabergoline and Bromocriptine. The uniqueness of this case is attributed to t...

Introduction: Primary Hypothyroidism is a commonly encountered endocrine disorder and can be associated with pericardial effusion and cardiac tamponade in severe cases. Early detection of Hypothyroidism is key since it is a potentially treatable and reversible cause of pericardial effusions.Case Presentation: A 53-year-old female was admitted following a fall. Clinical history was remarkable with symptoms of persistent t...