Endocrine Abstracts

Background: There is growing evidence that adhesion molecules, proinflammatory cells and cytokines play an important role in a variety of cardiac pathophysiological conditions; Cytokines are responsible for the modulation of immune and inflammatory processes. It has been suggested that cytokines such as IL-1, IL-2, IL-6, IL-10 and TNF alpha are important modulators of atherosclerotic effects with IL-2 and Interferon γ having a proinflammatory atherogenic effect and IL-8 a...

Cytokines play a role in cardiovascular diseases by inducing inflammation, cell proliferation and apoptosis. It is well known that activated macrophages are one of the main sources of inflammatory cytokines. Previous studies have shown that the cells found in the vascular wall produce various kind of cytokines which are involved in cardiovascular diseases. It has been reported that some cytokines (IL-6, IL-8) are increased in acute coronary syndrome. The results of some other ...