ea0011p6 | Bone | ECE2006
Angelopoulos N
, Rombopoulos G
, Kaltsas D
, Kaltzidou V
, Katounda E
, Tolis G
Objectives: To characterize the possible role of the osteoprotegerin (OPG) and receptor activator of NF-κB ligand (RANKL) system in thalassemia-related bone loss.Background: Osteoporosis represents an important cause of morbidity in patients with β-thalassemia major and its aetiology is multifactorial.Methods: Serum concentrations of OPG, RANKL, markers of bone turnover and lumbar spine bone mineral density (BMD) were mea...