Endocrine Abstracts

Introduction: Medullary thyroid carcinoma (MTC) could be familial in 30% of cases. Here, we report a family of FMTC with rarely seen RET p.S891A mutation.Case presentation: A 49-year-old man presented with a single nodule in the left lobe of thyroid. Thyroid ultrasonography (US) showed a nodule and pathological cervical lymph nodes. There was no relevant family history. Fine-needle aspiration cytology (FNAC) of the nodule was consistent with a diagnosis ...

Background and aim: Acromegaly is a rare endocrine disease and is associated with an increased prevalence of colorectal cancer and pre-malignant tubular adenomas, and also may be associated with other organ malignancies such as breast and thyroid. We report a rare case of acromegaly concomitant with adenocarcinoma arising from pancreas.Case report: A 52-year-old man who was diagnosed with acromegaly two years ago referred our outpatient clinic. After dia...

Background: Although very rare, insulinomas are the most commonly occurring endocrine tumor of the pancreas. The aim of this study was to review the clinical presentation, diagnostic approach and management of patients with an insulinoma.Methods: 22 insulinoma patients, with an age range of 20–79, were included and evaluated according to their clinical presentation, blood biochemistry, imaging studies, operative management, pathological manifestatio...

We planned to research the effect of the regular exercise of type 2 diabetes mellitus (DM) patients on metabolic control, malondialdehyde (MDA) as the oxidative stress marker and on the quality of life. The study has been carried out 64 patients diagnosed with Type 2 DM for at least 6 months, without any microvascular/macrovascular complication for diabetes, using oral anti-diabetic agent with a HbA1c value of less than 9%. The 31 patients were asked to carry out aerobic exerc...

Introduction: In this study, we aimed to examine the weight alterations after the medical treatment and compare the effects of medical treatment in obese patients who applied to Endocrinology Policlinic.Material and method: We examined the patients who were diagnosed as obesity and initiated medical treatment at Endocrinology and Metabolism Diseases Policlinic in Inonu University Medical Faculty between Agust 2005–May 2008. Patients were divided int...

Objectives: Acromegaly may arise with several clinical presentations and cardiac involvement is the most important factor affecting the course of the disease.Case: A 32-years old man admitted to hospital complaining with shortness of breath. After initial evaluation he was diagnosed as ‘cardiac failure’. Cardiac evaluation revealed that he had ‘dilated cardiomyopathy’ with ejection fraction (EF) of 20%, global hypokinesia without valv...

Introduction: Autoimmune thyroiditis (AIT), also called Hashimoto thyroiditis or chronic lymphocytic thyroiditis is characterized by destruction of the thyroid gland involving apoptosis of thyroid epithelial cells. It usually presents as euthyroidism or subclinically hypothyroidism, rarely as overt hypothyroidism. The cause of Hashimoto’s thyroiditis is thought to be a combination of genetic susceptibility and environmental factors. Bisphenol A (BPA), an endocrine-disrupt...

Previous studies have shown increased hypoglycemia-associated cardiac arrhythmia and mortality in patients with type 2 diabetes and cardiovascular disease.In this study, we aimed to evaluate the response of gastrointestinal hormones and glucoregulatory hormones to the oral glucose tolerance test in patients who were diagnosed with reactive hypoglycemia and to evaluate the risk of arrhythmia with long-holter ECG measurements in patients with a diagnosis o...

Introduction: Both endothelial dysfunction and albuminuria have been shown to be related to cardiovascular risk. We aimed to investigate relations between endothelial dysfunction, albuminuria and frequency of the microvascular complication in type 2 diabetic patients.Method: Forty type 2 diabetic patients (24 microalbuminuria and 16 macroalbuminuria) with a mean age of 57.2±10.8 years and 25 healthy control subjects with a mean age of 54.1±9.6 ...

Background: Studies on thyroid hormones in obese adult patients are contradictory. Moreover, little is known about the effect of weight loss on thyroid functions. Thus, we aimed to investigate thyroid hormone status, and possible effect of weight loss on thyroid hormones in obese patients.Methods: We study population consisted of 39 (35 female, 4 male) euthyroid obese patients with mean age 42.76±10.52 years. Of these 19 patients were morbid obese. ...