Endocrine Abstracts

Background: Depressive symptoms (DS) and diabetes-related distress (DD) are common comorbidities in diabetic patients adversely affecting diabetes self-management and patients’ well-being.Aim: To examine associations between DS and DD with glycaemic control, quality of life and diabetes self-management.Materials and methods: Depressive symptoms, DD, quality of life, diabetes self-management and metabolic indicators were asses...

: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. It’s a heterogeneous functional disorder of unclear etiology. The features of PCOS are disorders of ovulation, androgen excess, polycystic ovaries; it’s associated with presence of associated risk factors for cardiovascular disease (obesity, glucose intolerance, dyslipidemia). The diagnosis of PCOS is made using the Rotterdam 2003 criteria. 23yo female patie...

Disturbances of thyroid hormones produce clinical symptoms but hormonal level at which this happens vary from patient to patient. In order to determine how much hormonal change patients can tolerate before developing symptoms we retrospectively collected data of 86 hyperthyroid and 48 hypothyroid patients, 120 females and 14 males aged 28–85 and 23–74 yrs respectively. We included only patients who at some time during treatment had abnormal values of TSH and/or thyro...

Introduction: We evaluated the efficiency of TESA–ICSI method in infertile men with obstructive azoospermia. Testicular spermatozoa are obtained by fine-needle aspiration of testis (23 G) and than injected into cytoplasm of the oocyte.Methods: In the study, there were 173 married couples with 253 attempts of artificial fertilization (1.45 attempts per couple). Average age of women were 31 years and of men 36 years. Obstructive azoospermia was detect...

In order to compare effects of treatment in hyperthyroid patients treated with thyrostatic drug alone and those treated with thyrostatic plus levothyroxine we reviewed data from 60 consecutive patients attending our outpatient clinic. 27 patients, 25 ♀ and 2 ♂, aged 27–68 years were treated with thyrostatic drug alone, while 33 patients, 31 ♀ and 2 ♂, aged 19–88 years received thyrostatic plus levothyroxine. Number of remissions was greate...

We retrospectively collected data from 62 pregnant females who were followed for hyperthyroidism (n=17), hypothyroidism (n=21), euthyroid Hashimoto’s thyroiditis (n=9), and simple goitre and other non-autoimmune thyroid diseases (n=15).Among them 33 showed at least once during pregnancy low FT4, or low FT3 and FT4 in total on 74 occasions. Low FT4 was found on 15, low FT3 on 15 and low FT<s...

Last 10 years, we are living in iodine sufficient environment. To clarify natural course of thyroid autonomy in this conditions, we investigated 100 consecutive patients in last three months – 93 female and 7 male aged 19–86 years. Included were patients with scans showing thyroid autonomy, and patients with nodular or diffuse goiter with low or suppressed TSH. We followed them from their first visit. Thirty patients were hyperthyroid – one spontaneously cured, ...

Level of pituitary trophic hormone dictates dose of hormone replacement (HRT) in endocrine gland hypofunction. We examined 28 women receiving HRT in postmenopausis aged 46–63 yrs (54±4.27 yrs). In average patients started HRT two years after last spontaneous menstrual bleeding (28±3.76 months, 1–132 months). 8 patients used transdermal estradiol, 10 peroral combination of estradiol, estriol and norethisterone and 10 patients were treated by fixed peroral co...

Objective: To analyse the semen quality in patients with newly diagnosed lymphoma’s before starting the treatment.Materials and methods: We evaluated semen quality in 131 patient with lymphoma who underwent sperm banking in our clinic over a 14-year period. 102 patients had Hodgkin’s lymphoma, and 29 had non-Hodgkin’s lymphoma. Semen samples were collected by masturbation after 2–7 days of sexual abstinence. Age at banking, semen volu...