Searchable abstracts of presentations at key conferences in endocrinology

ea0011p431 | Endocrine disruptors | ECE2006

Extracts of black cohosh (Actaea racemosa) inhibit growth of MCF-7 and MDA-MB-231 breast cancer cells and dose-dependently inhibit oestrone sulphatase activity

Whitehead SA , Kotalla C , Rice S , Mason HD

Extracts of black cohosh (BCE) are frequently used as an alternative to conventional HRT to treat menopausal symptoms, particularly in Germany and the United States. In fact, BCE is the 14th most popular herbal product in the US and in 2003 sales were at least $15.7 million. Evidence for an increased incidence of breast cancer in long-term users of HRT has reduced its use and may increase the use of alternative treatments. These still require rigorous scientific investigation,...