Searchable abstracts of presentations at key conferences in endocrinology

ea0011p454 | Endocrine tumours and neoplasia | ECE2006

Sustained correction of hypercortisolism with a low dose mitotane regimen in a young woman with PPNAD and Carney Complex

Campo M , Picca G , Laudadio ED , Lamacchia O , Cignarelli M

A 27-year-old woman with Carney Complex, with inactivating mutation of the PRKAR1α gene [(a 2-bp deletion of nucleotides T and G at positions 576 and 577 with frame-shift mutation beginning with aminoacid residue threonine 163 (ΔFSterThr163)], bearing a GH secreting microadenoma, Cushing syndrome from PPNAD and with high operatory risk because of the neurological sequelae of cerebral embolism from atrial myxomas, underwent a low-dose mitotane (MT) regimen.<p clas...