Endocrine Abstracts

Abstract unavailable at the time of publishing...

A 50-year-old woman with learning difficulties and schizophrenia presented to accident and emergency with 5 days of epigastic pain and vomiting.Initially, she was peripherally shut down, with a pulse of 120 and blood pressure of 115/80. Chest examination was normal. Abdominal examination showed epigastric tenderness with guarding.Blood tests confirmed a diagnosis of acute pancreatitis (Amylase 1972 IU/l), with hypercalcaemia (corre...

We describe the symptoms and review the laboratory findings in a case of patient with Mauriac syndrome.A 19 years old Type 1 diabetic male with past history of multiple admissions to intensive therapy unit (ITU) with diabetic ketoacidosis (DKA) in a period of 3 years was admitted to ITU with DKA. On his examination protuberant abdomen with hepatomegaly, cushingoid feature, normal BMI and growth impairment were seen. His sexual development was normal. He ...

There is clear evidence in humans that stress during pregnancy has negative consequences on the foetus leading to greater susceptibility to disorders such as heart disease, diabetes type II and anxiety in adulthood. We aimed to assess whether stressors experienced by commercial pigs have a detrimental impact on piglet behavioural and neurophysiological development. Thirty-six primiparous sows were divided into control and two mixed groups that were stressed (social mixing) dur...

A 70-year-old woman presented with low back pain. A diagnosis of discitis (L4-L5) was made and the patient was started on IV flucloxacillin 1 g every 6 h and fusidic acid. The back pain was improving and the serum electrolytes were all within normal range with potassium level at 4.4 mmol/l (normal: 4.0–5.5) and magnesium at 0.68 mmol/l (normal: 0.7–1.1). However two weeks after starting the IV flucloxacillin, the patient’s electrolytes showed a persistent hypoka...

Case history: A 28 year-old male of British origin was referred with a one-year history of a left-sided chest mass and an abnormal chest X-ray. He was otherwise fit and well, had a past medical history of vitiligo and had no relevant family history. His physical examination revealed some hypopigmented spots on his skin, several tattoos across his back and a firm mass on his left upper chest, which was mildly tender on palpation. He had no other palpable masses.<p class="ab...

We present a 59-year-old lady referred to us with worsening fatigue, arthralgia and dizziness over several years. Other symptoms included sleep disturbance, headaches, occasional palpitations and sore eyes. There was no family history of thyroid illness. Her medications included Vitamin B, Vitamin C, Hi 5 vitamin supplement, calcium, and zinc. On further questioning, she was taking kelp supplement (2 tablets per day) as recommended by a nutritionist, for treatment of ‘slu...

Background and aims: Antithyroid medications are first line treatment for thyrotoxicosis in the UK. The risk of agranulocytosis is ~1:2000 cases. Between 1963 and 2003, 809 adverse reactions related to antithyroid medications were reported. Of these 179 were due to agranulocytosis. Forty-two fatal events were recorded and half of these were related to agranulocytosis.Patient awareness is vital in preventing drug associated morbidity and mortality. We con...

A 59-year-old lady with headaches and malaise was found to be hypertensive with a blood pressure (BP) 210/105. An MRI brain revealed a haemorrhagic lesion in the right temporal lobe. There were no other signs of end organ damage. Her medications included atenolol 25 mg OD, ramipril 10 mg OD and bendroflumethiazide 2.5 mg OD. It transpired that she has been drinking 5 cups of liquorice tea per day over the last 18 months. Following a vomiting illness she stopped liquorice tea c...

A 71-year-old man with carcinoma of prostate and bony metastasis, presented with acute bradyarrhythmia, severe hypocalcaemia and acute renal failure 72 h after intravenous infusion of zoledronate. Before therapy, serum calcium was 2.14 mmol/l (normal, 2.10–2.55 mmol/l), serum phosphate 1.4 mmol/l (normal, 0.8–1.5 mmol/l), serum creatinine 95 umol/l and eGFR 74 ml/min. 25OH vitamin D was not measured. Three days later he presented with a syncopal episode. Initial bloo...