Searchable abstracts of presentations at key conferences in endocrinology

ea0032p191 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2013

Pentraxin-3 as a more sensitive marker of coronary artery disease severity than C-reactive protein

Szkodzinski Janusz , Hudzik Bartosz , Danikiewicz Aleksander , Pietka-Rzycka Anna , Lekston Andrzej , Zubelewicz-Szkodzinska Barbara

Introduction: Pentraxin-3 (PTX3) is an acute-phase reactant that shares structural and functional homology with C-reactive protein (CRP). However, unlike CRP, which is synthesized mainly in the liver, PTX3 is produced at the site of inflammation. It has been suggested that PTX3 plays the same role in the periphery that CRP does in circulation. PTX3 may represent a rapid marker for local inflammation.Methods: Fifty three patients with stable coronary arte...

ea0011p218 | Cytokines and growth factors | ECE2006

The role of IL-4 and IFN-gamma as prognostic factors of major adverse cardiac events in patients with ST-elevation myocardial infarction assigned primary percutaneous coronary intervention

Osuch M , Szygula-Jurkiewicz B , Szkodzinski J , Wojnicz R , Lekston A , Polonski L , Blazelonis A , Zubelewicz-Szkodzinska B

Mediators of inflammatory reaction are present at every stage of forming of atheromatous plaque, its proliferation and destabilization. Cytokines play a key role in regulation of intensity of chronic inflamatory reaction. We aimed at investigation if IL-4 and IFN-gamma are predictors of MACE in a group of patients with acute myocardial infarction (AMI).A total of 50 patients: 40 males and 10 females, aged 56±10 years (mean±S.D.),...