Abstract Search

ea0011p128 | Clinical case reports | ECE2006

Time course of neuroendocrine dysfunction after aneurysmal subarachnoid hemorrhage – need for reassessment even years after the hemorrhage?

Reineke A , Poll E , Levasseur S , Yagmur E , Gilsbach JM , Kreitschmann-Andermahr I

In recent years there has been increasing evidence for neuroendocrine dysfunction as a sequel of aneurysmal subarachnoid hemorrhage (SAH). One investigation has assessed pituitary function in SAH-survivors in a longitudinal design 3 and 12 months after the hemorrhage, but nothing is known about the dynamics of the hypothalamo-pituitary axis in the years following the bleeding. We present the data of 5 patients who had sustained aneurysmal SAH and had undergone their first endo...

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ea0081oc2.2 | Oral Communications 2: Adrenal and Cardiovascular Endocrinology 1 | ECE2022

Loss of SUMO-specific protease 2 leads to adrenal insufficiency limited to glucocorticoids

Dufour Damien , Dumontet Typhanie , Sahut-Barnola Isabelle , Onzon Meline , Pussard Eric , Wilmouth Jr James , Olabe Julie , Levasseur Adrien , Bossis Guillaume , Yeh Edward , Val Pierre , Martinez Antoine , Anne-Marie Lefrancois-Martinez

The adrenal gland produces corticosteroids essential for hydromineral and metabolic homeostasis. It is organised, in mice, in two concentric layers. The zona glomerulosa (zG) and fasciculate (zF), renewed from progenitors located in the capsular periphery. Centripetal renewal and maintenance of cortical zonation are dependant of a balance between WNT/β-catenin and ACTH/PKA signalling pathways. They provide recruitment and consecutive differentiation of progenitors into zG...

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Endocrine Abstracts

Time course of neuroendocrine dysfunction after aneurysmal subarachnoid hemorrhage – need for reassessment even years after the hemorrhage?

Loss of SUMO-specific protease 2 leads to adrenal insufficiency limited to glucocorticoids

BiosciAbstracts