Endocrine Abstracts

Acute presentation: 46 year old patient was admitted as an emergency with vomiting, hypotension and serum cortisol of 26 nmol/L indicative of adrenal failure. Despite previous history of panhypopituitarism he was found to be hyperthyroid (free T4 6.32 ng/dL (0.93-1.7), free T3 22.21 pg/mL (1.8-4.6)).Past Medical History: He was fit & well till the age of 45. Eight months prior to this hospitalisation he presented with diabetes insipidus and was found...

Background: Neck irradiadion is associated with several complications including both hypo- and hyperthyroidism. We present a case of severe hypothyroidism, followed 5 years later by thyrotoxicosis.Case description: A 27-year-old female presented with clinical and biochemical thyrotoxicosis (TSH 0.01 μIU/ml (ref. range: 0.27–4.2 μIU/ml); FreeT4 1.58 ng/dl (ref. 0.98–1.63 ng/dl); FreeT3 4.56 pg/ml (ref. 2.6–4....

Background: Successful parathyroidectomy depends on recognition and excision of all hyperfunctioning parathyroid glands.The aim of the study was to estimate the diagnostic value of PTH concentration in the needle washout after fine-needle aspiration of foci suggestive of enlarged parathyroids in patients (pts) with hyperparathyroidism (HP).Material and methods: Of 18 pts were studied (15 females, 3 males); 16 pts with primary HP (t...

The effectiveness of thyroid remnants ablation with 131I after thyroidectomy for differentiated thyroid carcinoma (DTC) depends mainly on absorbed radiation dose, which is proportional to 131I uptake (Tup) and its effective half-life time (EHL) in the remnants.Aim: Assessment of endogenous TSH level increment effects on EHL of 131I and Tup in thyroid remnants after surgery for DTC.Material: Twenty-o...

Introduction: Characteristic localisations of metastases of differentiated thyroid carcinoma (DTC) include local lymph nodes, the lungs and bones, while the incidence of DTC metastases onto the liver, the brain and skin is clearly lower. The localisation of metastases in other organs, including the kidneys, is very rare.Material and methods: A case of a 73–year-old patient with thyroid oxyphilic carcinoma is reported, the case being diagnosed in 199...

Introduction: An increase of thyroid iodine uptake (Tup) is one of the symptoms of thyrocyte stimulation by means of recombinant human thyrotropin (rhTSH). Low Tup, characteristic of iodine induced hyperthyroidism, creates serious problems, when 131I is considered, making this kind of treatment difficult, if not impossible.Material and methods: We report a case of a 74 years old patient, with hyperthyroidism, induced by amiodarone administrati...