Searchable abstracts of presentations at key conferences in endocrinology

ea0011p516 | Endocrine tumours and neoplasia | ECE2006

mRNA expression of somatostatin receptor subtypes in pheochromocytomas/paragangliomas

Mannelli M , Gelmini S , Malentacchi F , Simi L , Gaglianò MS , Ercolino T , Becherini L , Valeri A , Pratesi C , Orlando C

Somatostatin (sst) receptors are expressed in many tissues and multiple subtypes are often present in the same cells. Their activation by endogenous sst as well as by sst-analogues leads to inhibition of secretion and growth in some tumor, such as the neuroedocrine ones.Pheochromocytomas (Pheos) and paragangliomas (PGLs) are neural crest-derived tumors which can be sympathetic or parasympathetic in origin and present themselves as sporadic or familial. T...