ea0011p516 | Endocrine tumours and neoplasia | ECE2006
Mannelli M
, Gelmini S
, Malentacchi F
, Simi L
, Gaglianò MS
, Ercolino T
, Becherini L
, Valeri A
, Pratesi C
, Orlando C
Somatostatin (sst) receptors are expressed in many tissues and multiple subtypes are often present in the same cells. Their activation by endogenous sst as well as by sst-analogues leads to inhibition of secretion and growth in some tumor, such as the neuroedocrine ones.Pheochromocytomas (Pheos) and paragangliomas (PGLs) are neural crest-derived tumors which can be sympathetic or parasympathetic in origin and present themselves as sporadic or familial. T...