Endocrine Abstracts

The occurrence of thyroid diseases is determined by interplay between genetic and environmental factors. The major environmental factor that determines goiter prevalence is iodine status.Thyroid nodules are present in up to 30% of the Georgian population. The causative role of iodine deficiency which is still endemic in this country has long been established.Fine-needle aspiration biopsy (FNAB) of the thyroid gland is the cost-effe...

Deficient production of thyroid hormones in maternal organism may have a drastic impact on brain development of the offsprings. Among the people originated from the regions with essential deficiency of iodine in foodstuff there is a high chance for prevalence of mental retardation and neurological cretinism with all possible complications.The present study analyses changes in emotional state (open field testing), learning ability and memory processes (ma...

Numerous number of studies indicate significant role of oxidative stress in the pathogenesis of thyrotoxicosis. The aim of this work was to estimate oxidative metabolism changes in myocardium and effectiveness of olygocrine in the experimental model of thyrotoxicosis.Methods: Thyrotoxicosis was induced in mature white wistar rats by daily administration of L-thyroxine (100 μg/100 g). We have conducted 3 series of experiments studying: (1) effects of...

Introduction: In this report, we describe a rare coexistence of a multifocal papillary thyroid (micro)carcinoma and aldosterone-producing adenoma.Case presentation: A 60-year-old man attended our clinic with a mass in the right adrenal gland was identified during the work-up in 2007. The patient presented complaints on anxiety, tachycardia, and arterial hypertension. He had several episodes of severe hypertension (220/120 mmHg) while sleeping. In 2014, a...

The prevalence of cardiovascular diseases (CVD) has increased sharply in the developing countries and because Type 2 diabetic patients are at increased risk for CVD.Objective: To determine the prevalence of patients with past hystory of a myocardial infarction or cerebral strok in newly diagnosed type 2 diabetic patients in Georgia.Design: Cross-sectional study.Patients: Newly diagnosed type 2 diabetic patien...