Endocrine Abstracts

Introduction: Acromegaly usually results from GH hypersecretion elaborated by somatotrop adenoma. The occurrence of a pregnancy in an acromegaly is an infrequent event, but better described in recent years. It could be aggravate GH secretion and tumor volume.Objective: Describe eight pregnancies including twin pregnancy in six acromegalics patients hospitalized in the endocrinology department of the Pierre and Marie Curie center in Algiers.<p class="...

Adrenocortical tumor is a rare malignant tumor of adrenal location. With a poor prognosis that can be improved by rapid diagnosis and adequate early management, hence the importance to evoke this etiology in front of any atypical adrenal mass or any suggestive clinical or biological context. The objective of our modest work is to report through a retrospective study the profile of adrenocortical tumors treated in our service over a period of 13 years from 2007 to 2020. Thirty ...

Introduction: The sellar plasmacytoma, an exceptional localization that can be solitary or associated with a multiple myeloma. We report the case of a sellar mass wrongly diagnosed as an invasive non-functional pituitary adenoma, the diagnosis was rectified postoperatively by the anatomopathological study.Case description: A 44 year old female patient, with history of cholecystectomy and megaloblastic anemia, was referred to our center for management of ...

Introduction: Langerhans cell histiocytosis (LCH) is a systemic disorder characterized by clonal proliferation of immature dendritic cells observed mainly in children. The affection of the sellar region in adults with central diabetes insipidus as the first manifestation of the disease is extremely rare creating a problem of etiological diagnosis especially when central diabetes insipidus (CDI) is apparently isolated.Case description: A 21-year-old man w...

Introduction: As an alternative to cortisol assays in the serum or saliva to diagnose hypercorticisme we evaluated the ability of a commercial cortisol assay to assess capillary blood cortisol concentrations using routine procedures.Methods: Capillary blood was obtained using a device used by diabetics to routinely assess capillary glucose levels and deposited on Schleicher-Scheull 903 blotter paper (routinely used for neonatal diagnosis of hypothyroidis...

IntroductionPituitary apoplexy is a rare endocrine and neurosurgical emergency. It corresponds to the occurrence of an hemorrhage or infarction in the pituitary gland, or most often within a pituitary adenoma. The usual presentation associates sudden headaches, visual disturbances, altered consciousness and endocrine disorders wich are dominated by corticotropic insufficiency. We present two cases of pituitary apoplexy, the first one complicating an unde...

Introduction: The diabetic foot osteoarthropathy is defined as a progressive painless arthropathy of one or more joints due to an underlying neurological injury. It is the bed of complications and severe foot infections and involves the functional prognosis. Through observations of patients we report the difficulty of management of wounds on foot osteoarthropathy.Observation: It is five diabetic patients hospitalized in our department with an array of se...

Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder affecting women in reproductive age. Women with PCOS exhibit 2-3x higher levels of circulating Anti-Müllerian Hormone (AMH) as compared to healthy women and it is unclear if the elevation of AMH is a bystander effect or is driving the condition. Moreover, PCOS has a strong heritable component, however the etiopathology of the disease and the mechanisms underlying its transmission remain t...