Searchable abstracts of presentations at key conferences in endocrinology

ea0066d1.2 | (1) | BSPED2019

Natarajan Anuja

Anuja Natarajan completed her training in Paediatric endocrinology in 2004 and joined the Doncaster & Bassetlaw Hospitals NHS Foundation Trust (now a teaching hospital since 2018) in 2014 as a Consultant paediatrician with CCST in Endocrinology . She took up the post of lead for Paediatric diabetes and Paediatric Research in 2005 and since then has been in post for these two areas. Within the scope of her role as research lead Anuja has been successful in getting funding f...

ea0078p6 | Adrenal | BSPED2021

Diagnostic utility of cortisol responses to assess adrenal insufficiency using the GST – pilot study and literature review

Firth Anna , Natarajan Anuja

Background: The glucagon stimulation test (GST) involves administering an injection of glucagon and monitoring respondent levels of cortisol, growth hormone and glucose in the blood. The levels recorded are compared to current standard recommendations in order to offer a suggestion into growth hormone or cortisol deficiency. Many children who underwent the GST to investigate growth hormone deficiency (GHD) or prior to transfer to adult endocrine clinic failed to reach the adeq...

ea0036oc5.1 | Oral Communications 5 | BSPED2014

Congenital adrenal hyperplasia: a survey on the current practice in UK

Niranjan Usha , Natarajan Anuja

Introduction: Congenital adrenal hyperplasia (CAH) varies significantly in clinical presentation and progression causing challenges in management. The ultimate goal of treatment is to achieve normal growth and development while avoiding adrenal crisis and hyperandrogenism.Aim: Our aim was to ascertain the current practice in the UK on CAH management in children and compare these with the endocrine society recommendations.Methods: A...

ea0023p33 | (1) | BSPED2009

Is There A High Incidence Of Graves' Disease In Doncaster And What Are The Potential Causes? A Retrospective Study

West James , Natarajan Anuja

Graves’ disease is the most common cause of hyperthyroidism in children. The incidence in the UK and Ireland is unknown but estimated to be 0.84 per 100 000 people (0–15 yr olds). Due to an apparent high local incidence, a retrospective study was conducted on patients diagnosed with Graves’ disease in a district general hospital in the locality.Aim: To evaluate the clinical features, investigations and treatment of patients diagnosed from ...

ea0045p2 | Adrenal | BSPED2016

Assessment of staff knowledge of the management of acute illness in children on long term steroids in a large DGH offered Tertiary Paediatric Endocrine services

Newsome Helen , Natarajan Anuja

Introduction: Children on long-term steroid treatment are at risk of developing an Addisonian crisis during an acute illness unless their steroid dose is increased appropriately. It is essential for all staff involved in the care and management of such patients (Paediatric Nurses, Paediatric Doctors, ED Doctors) to be familiar with the relevant management guidelines.Methodology: Between November 2015 and May 2016 Paediatric and ED nursing and medical sta...

ea0024p9 | (1) | BSPED2010

Classical CAH due to a rare compound heterozygote mutation masquerading as pubarche in a 3 years old girl

Sachdev P , Dane C , Natarajan A

Background: Congenital adrenal hyperplasia, (CAH) is a common autosomal recessive condition, 95% of which is attributable to mutations in the 21-hydroxylase (CYP21) gene. There is a wide range of clinical features and genotype phenotype correlations for common mutations are well described.Case: EG presented to the endocrine clinic at the age of 3.5 years with pubarche of 6 months duration and Tanner staging of PH3, B1and clitoromegaly (Prader stage 1) Ur...

ea0066p30 | Diabetes 2 | BSPED2019

Perceptions of multi-disciplinary team members and their roles: a survey of 82 carers and patients

Low Allison , Whinfrey Lisa , Natarajan Anuja

Background: Patients and carers encounter a range of diabetes multi-disciplinary team (MDT) members. Patients in focus groups have indicated that nurses are more approachable than doctors1, and the presence of specialist nurses in the MDT improves glycaemic control2. Nurses are perceived to be the core providers of diabetes care but this has not been quantified, nor have the perceived roles of other members of the MDT been explored....

ea0039ep79 | Miscellaneous/other | BSPED2015

The not so sweet truth of paediatric hypoglycaemia

Ramsden Louise , Wright Katherine , Natarajan Anuja

Introduction: Paediatric hypoglycaemia is a relatively common medical emergency. In order to allow identification of the underlying cause, investigations need to be performed urgently prior to treatment being given. If done correctly this can save the need for future investigations. A ‘hyposcreen’ costs ~£450 so careful consideration is needed to ensure correct patient selection, as inadequate investigations have further cost and patient safety implications....

ea0019p108 | Clinical practice/governance and case reports | SFEBES2009

Case of persistent mild hypocalcaemia? Carbamazepine induced osteomalacia

Natarajan G , Foster M , Zacharia S

A 41-year-old female was diagnosed with generalised seizures in 1984 and her EEG showed excess slow wave activity in the temporal region. She was commenced on carbamazepine. In 2005 she was diagnosed to have a bipolar affective disorder for which olanzapine was added.She was found to be hypocalcaemic with corrected calcium of 2.08 mmol/l in 2005 after sustaining a right undisplaced distal radial fracture following a seizure. She was empirically commenced...

ea0065p418 | Thyroid | SFEBES2019

‘Toxic adenoma; biopsy or not to biopsy?’

Arshad Muhammad Fahad , Natarajan Anuja , Debono Miguel , Balasubramanian Saba P

Toxic adenomas nodules rarely harbour cancer. Fine needle aspiration (FNA) is often not done due to the rarity of these lesions being cancer, the difficulty in interpreting cytology in hyperthyroid patients and the rarely reported instance of precipitating thyrotoxicosis. Here, we present two young Caucasian female patients with toxic adenomas, who underwent hemithyroidectomy and the histology unexpectedly revealed differentiated follicular cancer. The first is a 29-year-old p...