Endocrine Abstracts

Hyperthyroidism in Graves’ disease (GD) is caused by thyroid-stimulating autoantibodies to the TSH receptor. Hypothyroidism in Hashimoto’s thyroiditis (HT) is associated with thyroid peroxidase and thyroglobulin autoantibodies. Transformation of HT to GD has been rarely reported. We report a woman with history of HT, who then developed GD.Case presentation: A 50-year-old female with a past history of hypothyroidism due to HT treated with Levo...

Background: The diagnosis of Cushing’s syndrome is based on clinical suspicion and biochemical confirmation. Most cases are caused by an ACTH secreting pituitary microadenoma. In its severe form and when untreated, Cushing’s syndrome is associated with high mortality. We report a case of untreated Cushing’s syndrome due to pituitary microadenoma 8 years after the earlier manifestations.Observation: A 21-years-old woman was referred for pro...

Hyperthyroidism is rarely associated with malignancy. Some cases of co-existing between hyperthyroidism and thyroid carcinoma have been described. We report a case of association of a toxic thyroid nodule and papillary microcarcinoma.Observation: A 50-year-old male was referred to the endocrinologist for hyperthyroidism (TSH: 0.01 mUI/l, FT4: 22.8 pmol/l, FT3: 17.1 pmol/l). Thyroid ultrasonography showed a nodule of 38 mm in the left lobe. 99 mTc thyroid...