ea0020p77 | Thyroid | ECE2009
Szczepanek Ewelina
, Ruchala Marek
, Szaflarski Witold
, Budny Bartlomiej
, Nowicki Michal
, Zabel Maciej
, Sowinski Jerzy
Thyroid hemiagenesis (TH) is a rare inborn anomaly presenting as failure of the development of one thyroid lobe. Recent research on the molecular background underlying thyroid dysgenesis have mainly focused on patients with congenital hypothyroidism; in contrast, subjects presenting TH were only sporadically involved. Changes in transcription factor genes, including TTF1, TTF2 and PAX8, which play an important role in thyroid embryogenesis, have been postu...