Endocrine Abstracts

Introduction: Effects of selected drugs on the efficacy of (131I) radioiodine therapy were examined.Material and methods: The study involved 200 hyperthyroid patients, treated with radioactive iodine. They were divided into five (5) groups (40 persons in each). In group I – beside 131I, patients were additionally administered antithyroid drugs, in group II – 131I and lithium carbonate, group III – 131<...

Introduction: The influence of demographic and clinical factors on the outcome of 131I therapy in hyperthyroid patients has been examined, based on a retrospective evaluation of results obtained in patients, submitted to 131I treatment. The goal of the study was an analysis of factors, including the age and sex of patients, disease duration time, as well the hormonal status before 131I application, which could have influenced the effects of the...

The effectiveness of thyroid remnants ablation with 131I after thyroidectomy for differentiated thyroid carcinoma (DTC) depends mainly on absorbed radiation dose, which is proportional to 131I uptake (Tup) and its effective half-life time (EHL) in the remnants.Aim: Assessment of endogenous TSH level increment effects on EHL of 131I and Tup in thyroid remnants after surgery for DTC.Material: Twenty-o...

Introduction: Characteristic localisations of metastases of differentiated thyroid carcinoma (DTC) include local lymph nodes, the lungs and bones, while the incidence of DTC metastases onto the liver, the brain and skin is clearly lower. The localisation of metastases in other organs, including the kidneys, is very rare.Material and methods: A case of a 73–year-old patient with thyroid oxyphilic carcinoma is reported, the case being diagnosed in 199...

Introduction: An increase of thyroid iodine uptake (Tup) is one of the symptoms of thyrocyte stimulation by means of recombinant human thyrotropin (rhTSH). Low Tup, characteristic of iodine induced hyperthyroidism, creates serious problems, when 131I is considered, making this kind of treatment difficult, if not impossible.Material and methods: We report a case of a 74 years old patient, with hyperthyroidism, induced by amiodarone administrati...

Introduction: Longitudinal bone growth ceases by the end of puberty, and the induction of epiphyseal maturation and closure is thought to be a result in both sexes of the action of increased pubertal oestrogen concentrations. However, bone mass accrual progresses beyond puberty and we related sex steroid hormones and sex hormone binding globulin (SHBG) levels to calcaneal quantitative ultrasound index (QUI) in young adult men.Methods: Eighty men aged bet...