Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep128 | Steroids, development and paediatric endocrinology | ECE2015

Is thyroid function related to masked hypertension?

Ates Ihsan , Altay Mustafa , Kaplan Mustafa , Ozkayar Nihal , Alaguney Erdem , Ozkayar Adem

Background: Thyroid hormones affect almost all the tissues of the body and their cardiovascular effects are very significant. The relationship between masked hypertension (MHT) and thyroid hormones is not known. Therefore, we sought to investigate any relationship between patients with MHT, newly diagnosed by home blood pressure monitoring, and thyroid hormones.Methods: Patients older than 18 years of age without a previous diagnosis of hypertension and ...

ea0037ep324 | Diabetes (pathiophysiology & epitemiology) | ECE2015

The relationship between higher left ventricular mass index and plasma total homocysteine levels in patients with type 2 diabetes mellitus

Kundi Harun , Ates Ihsan , Ozkayar Nihal , Ulusoy F Vasfi

Purpose: The aim of the present study was left ventricular mass index (LVMI) in type 2 diabetes mellitus (T2DM) patients may be related increased circulating homocysteine (Hcy) levels.Methods: The study group comprised 130 patients, and all patients were newly diagnosed with diabetes and were not taking any medication. Measures of left ventricular mass (LVM) were assessed using Devereux formula and left ventricular mass index (LVMI) was calculated as LVM...

ea0037ep1022 | Thyroid (non-cancer) | ECE2015

The serum irisin level in non-diabetic patients with chronic kidney disease

Ates Ihsan , Ozkayar Nihal , Topcuoglu Canan , Dede Fatih

Background and objectives: Our objective in this study was to discover the relationship of irisin hormone, which acts on adipose tissue and the metabolism as thyroid hormones, with the thyroid functions and the obesity secondary to thyroid disease.Methods: A total of 74 patients were included in the study, of the patients, 37 were newly diagnosed with Hashimoto’s thyroiditis dependent hypothyroidism but not received a treatment yet, and the remainin...

ea0037ep547 | Obesity and cardiovascular endocrinology | ECE2015

The relationship between the subclinical target organ damage and the levels of ischemia-modified albumin in hypertensive patients

Ozkayar Nihal , Ates Ihsan , Akyel Fatma , Tayman Cuneyt , Namuslu Mehmet , Barca A Nurdan , Akyel Serdar , Dede Fatih

Aim: To investigate the relationship between the presence of subclinical target organ damage (STOD) and the levels of ischemia-modified albumin (IMA) in hypertensive patients.Methods: The study included a total of 106 patients, 53 with STOD and 53 without STOD. STOD was deemed present if fundus examination revealed a grade 3–4 retinopathy; the left ventricular mass index (LVMI) was >95 g/m2 in females and >115 g/m2 in m...

ea0037ep548 | Obesity and cardiovascular endocrinology | ECE2015

The relationship between socioeconomic level, and the prevalence of masked hypertension and asymptomatic organ damage

Ates Ihsan , Altay Mustafa , Kaplan Mustafa , Ozkayar Nihal , Toprak Guvenc , Alaguney M Erdem , Ozkara Adem

Background: This study aimed to determine the prevalence of masked hypertension (MHT) and its association with asymptomatic organ damage (AOD) in a low socioeconomic district of Ankara, Turkey.Material and methods: Data obtained from the medical records of 712 patients with no known diagnosis of hypertension that presented to a polyclinic due to symptoms related to elevated blood pressure (BP) and were screened for MHT were retrospectively reviewed. The ...

ea0037ep361 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Dynamic thiol/disulfide homeostasis in patients with newly diagnosed type 2 diabetes mellitus

Bayrakci Nergiz , Ates Ihsan , Ozkayar Nihal , Yilmaz Fatma Meric , Topcuoglu Canan , Neselioglu Salim , Erel Ozcan , Altay Mustafa

Background: Thiol/disulfide homeostasis plays an important role in antioxidative defense mechanism, detoxification, signal transport, management of enzyme activity and trascription factors, and apoptosis. When thiol/disulphide homeostasis breaks down, these important cellular functions get deranged. Pathologies secondary to oxidative stress are seen in organeles in which this homeostasis is deranged. The aim of the study was to investigate dynamic thiol/disulfide homeostasis i...

ea0090p130 | Pituitary and Neuroendocrinology | ECE2023

Increased Plasma Leptin and Agouti-Related Peptide May Be Related To Sleep Alterations In Patients With Active Cushing’s Syndrome

Sulu Cem , Mefkure Ozkaya Hande , Kadioglu Pinar

Aim: To evaluate sleep architecture of patients with Cushing’s disease (CD) and to explore whether agouti-related peptide (AgRP) leptin, and interleukin-6 (IL-6) play a permissive role in sleep alterations.Methods: We performed polysomnography on 26 patients with active CD and age 26 age- and sex-matched control subjects. Blood samples were obtained from all participants for the analyses of AgRP, leptin, and IL-6. The laboratory and sleep-related pa...

ea0090p159 | Pituitary and Neuroendocrinology | ECE2023

Mild Autonomous Cortisol Secretion May Be Related To Decreased Thalamic Volume

Sulu Cem , Kadioglu Pinar , Mefkure Ozkaya Hande

Aim: To investigate the volumetric changes in cortical and subcortical deep gray matter (GM) structures and cognitive alterations in patients with mild autonomous cortisol secretion (MACS). We also sought to assess whether the anticipated changes in brain volume and cognitive functions of the patients with MACS differ from the changes in patients with overt Cushing’s Syndrome (CS). Methods: In this cross-sectional study, volumes of the cortex, hippo...

ea0016p774 | Thyroid | ECE2008

The variation intercellular adhesion molecule-1 level in primer and postoperative hypothyroid patients with treatment

Ozkaya Mesut , Cakal Erman , Yuzbasioglu M Fatih

Background and aims: It is reported that intracellular adhesion molecule-1 (ICAM-1) is important in autoimmune thyroid diseases also it is an important point that ICAM-1 level is high in postoperative hypothyroid cases. In literature, it is said that the level of plasma soluble ICAM-1 can be used as a evidence immune system activation and inflammation, and also it can be used for the diagnosis of some inflammatory and autoimmune diseases. The aim of our was to compare the leve...

ea0037ep901 | Thyroid cancer | ECE2015

Differentiated thyroid carcinoma in geriatric patients: a single centre experience with 7 years of follow-up

Ozkaya Mesut , Elboga Umut , Eraydin Ayten , Celen Y Zeki

Introduction: We evaluated the characteristics of differentiated thyroid carcinoma in geriatric patients and factors that influenced long-term survival in this retrospective study design. Among 1188 patients with differentiated thyroid carcinoma who were treated at our institution over the past 7 years, 144 patients were identified who were age 65 years or older(age range:65–88 years) at the time of their initial diagnosis. This study conducted a retrospective analysis of...