Endocrine Abstracts

Background:With respect to what has been mentioned about the progression of IGT to overt diabetes, and the lack of information in rural areas, and also some unresolved questions about the relationship between IGT and some micro and macrovascular complications, this research was accomplished in the years 2001-2002.Material and Methods:The first step of this study was carried out in 1977 to screen people (1988 ...

Background:With respect to what has been mentioned about the progression of IGT to overt diabetes, and the lack of information in rural areas, and also some unresolved questions about the relationship between IGT and some micro and macrovascular complications, this research was accomplished in the years 2001-2002.Material and Methods:The first step of this study was carried out in 1977 to screen people (1988 ...

Introduction: One of the most important methods for evaluation of treatment and care of diabetic patients is to assess the quality of life (QOL). The aim of this study is assess QOL and this dimensions and relational pattern between demographic characteristic.Method: This study is cross-sectional study wit convenience random sampling. The sample consisted 161 patients with type2 diabetic who refferd to diabetes center of Zanjan. Research instruments was ...

Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological entity characterized by seizures (91.7%), headache (83.3%), visual disturbance (62.5%),encephalophathy (29.2%), and paralysis (8.3%). Co-morbidities included systemic lupus erythematous (29.2%), kidney disease (20.8%), eclampsia(20.8%), renal artery stenosis (12.5%), Takayasu arteritis (4.2%), Sheehan's syndrome(4.2%), and acute intermittent porphyria (AIP) (4.2%). We report a 31-year-old woman w...

Introduction: Metabolic syndrome (MetS) consists of a constellation of metabolic abnormalities which include central obesity, hyperglycemia plus insulin resistance, high triglycerides plus low high-density lipoprotein (HDL) cholesterol and hypertension. A developing collection of proof proposes that metabolic condition is related to endocrine problems including thyroid brokenness. Thyroid brokenness in metabolic condition patients might additionally add to cardiovascular illne...

Introduction: Thyroid cystic nodules (TCN) are generally due to degenerative changes within colloid nodules or adenomas. True thyroid cysts are uncommon. But the prevalence of malignancy among TCN is controversial since some authors consider it to be low risk while some others consider it to have the same risks as malignancy as the solid lesions of the thyroid. Percutaneous ethanol injection (PEI) is utilised for treating benign cystic thyroid nodules. It is a protected option...

A 26-year-old man presented with a 3-month history of polydipsia, polyuria and nocturia. Physical examination was unremarkable. Random blood glucose was 5.1 mmol/l, sodium 147 mmol/l, serum osmolality 297 mOsm/kg, urine osmolality 81 mOsm/kg. A water deprivation test confirmed cranial diabetes insipidus. Magnetic resonance imaging (MRI) of his pituitary gland revealed nodular thickening of the pituitary stalk suggestive of inflammatory or neoplastic aetiology. He also complain...

Glycogen storage disease 1A (GSD1A) is an inherited metabolic disorder caused by glucose-6-phosphatase (G6PC) deficiency. Patients with GSD1A present disturbed glucose homeostasis and exhibit glycogen accumulation accompanied by hepatomegaly, hypoglycemia, lactic acidosis and hyperlipidemia. However, there are currently no licensed treatments for GSD1A, and human in vitro systems for disease modelling and drug screening are lacking. We aimed to develop a human hepatoc...

Background: There is a close association between low testosterone and metabolic syndrome. Testosterone replacement therapy (TRT) has beneficial effects on cardiovascular (CV) risk factors in men with hypogonadism.Aim: This is a retrospective audit of CV parameters in hypogonadal men treated with testosterone undecanoate (Nebido) in standard clinical practice.Methods: Patients with hypogonadism on testosterone undecanoate injections...

Back ground49, XXXXY syndrome is a rare defect of sex chromosomes frequently considered as a variant of Klinefelter syndrome. It is often associated with more severe dysmorphic features, hypogonadism, mental retardation, musculoskeletal abnormality, and rarely with diabetes mellitus due to insulin resistance.The goal: To describe clinical, biochemical, hormonal, radiological and developmental status of the patient with 49, XXXXY ka...