Endocrine Abstracts

Carney complex is a rare hereditary syndrome with an autosomal dominant inheritance pattern that manifests itself with a set of specific symptoms. Case presentation. 32-year-old woman was admitted to the endocrinological hospital with an active stage of acromegaly. From the anamnesis it is known that at the age of 11, the height was 172 cm. The diagnosis of acromegaly was established at the age of 28 years: IGF-1 673.8 ng/ml (78–311), pituitary gland with para(d)-sellar s...

The aim of the study is to estimate the efficacy of intravenous corticosteroid therapy in patients with active, sever Graves’ ophthalmopathy.Material and methods: 16 patients with bilateral active, sever Graves’ ophthalmopathy were included to the study. Euthyroididsm has been provided, mean dose of methimasol therapy was 9.4±6.6 mg a day, median of TSH- 0.3 mlU/l, median of fT4 –15.3 pmol/l. The median of duration of GO was 6.5 month...

Background: Acromegaly is an orphan neuroendocrine disease characterized by a variety of complications. Due to slow symptom progression acromegalic patients often are involved in growth hormone complications correction for a long time instead of search for main cause of these multiple disorders. A view on conductive hearing loss in acromegaly in literature is contradictory. The low incidence of hearing in acromegaly, compared with other complications, is presumably due to the ...

Background: Acromegaly is a neuroendocrine disease that occurs with slowly progressive symptoms, which leads to delayed diagnosis and the development of complications. Arthropathy is one of such complications, which is accompanied by severe pain and significantly worsens the quality of life. The main attention of researchers is devoted to the pathology of the hip, knee and hand joints. At the same time, the study of the shoulder, acromioclavicular, costovertebral joints in acr...

Aim: To estimate influence of radioiodine treatment of Graves’ disease (GD) on course of Graves’ ophthalmopathy (GO).Material and methods: 9 patients with GD and mild or moderate GO were included to the study (3 (33%) men and 6 (67%) women); the anamnesis of smoking had 4 persons (44%). Diagnosis of GO was evaluated by determination of severity and activity of disease with CAS, presents of diplopia, orbital ultrasound. CAS before radioiodine tr...