Searchable abstracts of presentations at key conferences in endocrinology

ea0011p813 | Thyroid | ECE2006

Liver enzymes alterations during high dose intravenous glucocorticoid pulse therapy for graves’ ophthalmopathy: frequency and putative risk factors

Altea MA , Morabito E , Menconi F , Piccione R , Latrofa F , Mazzi B , Bartalena L , Pinchera A , Marcocci C , Marinò M

Recently, we have reported a few cases of acute liver damage in patients with Graves’ ophthalmopathy (GO), during or following high dose intravenous (iv) glucocorticoid (GC) pulse therapy. In the present study we analyzed retrospectively liver enzymes (LE) in 294 consecutive patients with GO who underwent ivGC. LE were measured before or during ivGC, and in 91 patients also within 6 months after ivGC. An asymptomatic increase in LE (AST peak: 67–88 U/L, ALT peak: 75&...

ea0081p691 | Pituitary and Neuroendocrinology | ECE2022

Very-low-calorie-ketogenic-diet (VLCKD) approach to manage obesity in craniopharingioma patients

Ruxandra Cotta Oana , Alessi Ylenia , Certo Rosaria , Piccione Alessandra , Casablanca Rosalinda , Paola Giuseppe , Buda Martina , Scaramuzzo Monica , Ferrau' Francesco , Cannavo' Salvatore

Background: Craniopharingioma patients frequently experience severe obesity, unresponsive to caloric restriction or lifestyle modifications. Recently very-low-ketogenic-diets (VLCKD) proved to be a promising lifestyle intervention for obesity management, but no data are available regarding their effect on hypothalamic obesity (HO).Introduction: We present the outcome of VLCKD protocol applied in young patients with HO following neurosurgery for craniopha...