Endocrine Abstracts

Background: Turner syndrome (TS) is an important cause of short stature, however, there are a few reported cases of concomitant occurrence of TS and growth hormone deficiency (GHD).Case report: We report a 23-year-old female with concominat TS and GHD, also presenting partial FSH/LH deficiency and primary myxedema. The patient had iniatially been evaluated at the age of 15 for short stature and primary amenorrhea when she was diagnosed with Turner syndro...

Background: Carcinoid tumors are rare and slow growing malignancies derived from enterochromaffin cells. Two-thirds of carcinoid tumors arise in the gastrointestinal tract, and in 3% of these cases the primary site cannot be determined. Presenting symptoms depend on the location of the primary tumor may be nonspecific and in 13% of patients distant metastases are discovered on diagnosis.Case presentation: A 64 years old woman was admitted for diffuse abd...

Background: Pituitary apoplexy is a rare clinical syndrome manifested by rapid enlargement of a pituitary mass. When apoplexy occurs in functioning adenomas, it may result in spontaneous remission with or without associated hypopituitarism. Cases of recurrence in such patients are reported in literature.Case description: We present a case of a 44 years old male, overweight and dyslipidemic that presented to our clinic in 2016 and was diagnosed with acrom...

Hip fracture remains the most important clinical manifestation of osteoporosis, with many studies demonstrating a relationship between seasons and the incidence and mortality after hip fracture.Objective: We aimed to identify a seasonal variation (four seasons) in incidence of osteoporotic hip fracture admitted in trauma centers in Bucharest.Materials and methods: We observed the seasonal variation of 1176 patients, mean age 78.19+...

Carcinoid cardiac disease is a rare cause of intrinsic right heart valve disease with significant impact on mortality. We present the case of a young male patient (38 yrs old) complaining in the last 5 yrs of abdominal pain associated with flushing of the face that progressively worsened (up to 15 episodes/day) accompanied by diarrhoea and, in the last 2 months, by night sweats, distension of the abdomen, bilateral ankle swelling and progressive limitation in effort. Endocrine...

Background: Osteoporotic hip fracture remains a problem of public health concern. Different studies highlighted the existence of a particular epidemiology derived from local differences. We aimed to evaluate the epidemiology of osteoporotic hip fracture in the capital city of Romania plus city suburban area.Methods: We collected data from over 95 % of fractures from hospitals with an Orthopedic Surgery Department in the area of interest. Patients were se...

Introduction: Known as a potent anabolic drug, teriparatide has a stimulating effect on bone formation, increasing bone mineral density (BMD) and reducing fracture risk.Methods: 11 Caucasian women (mean age 66 years old) with severe osteoporosis treated with recombinant human parathyroid hormone (1–34) – teriparatide (Forsteo) 20 micrograms daily for 24 months were added to the study.BMD at lumbar spine, total hip and f...

Chronic kidney disease (CKD), with or without dialysis, often prompt biochemical tests for pheochromocytoma diagnosis due to high blood pressure, hemodynamic instability or association with certain genetic syndromes. Our objective was to assess plasma free metanephrine and normetanephrine in CKD disease patients, with or without dialysis.Methods: Plasma free metanephrine and normetanephrine were measured by an enzyme-linked immunosorbent assay in 42 pati...

Introduction: The prevalence of autoimmune disorders (AID) is more frequent in patients with Hashimoto’s thyroiditis (HT).Aim: To see if the clinical and biochemical aspects are different among the patients with HT and if they change related to the systemic or organ specific AID.Material and method: A. HT was diagnosed on antithyroperoxidase antibodies (ATPO) over 34 UI/ml. B. 491 patients with HT were investigat...

Objectives: To analyze the conceptual frame for a correlation between thyroid echographic description and antithyroid peroxydase antibodies (ATPO) levels in Hashimoto’s thyroiditis (HT).Material-methods: A. 783 patients: 396 with HT (ATPO>34 UI/ml), 386-control (ATPO<34 UI/ml). B. Ultrasound aspects were described in 8 patterns: 0-thyroid lack; 1 – hypoechogenic and pseudonodular; 2 – hypoechogenic and homogenous; 3 &...