Searchable abstracts of presentations at key conferences in endocrinology

ea0011p785 | Thyroid | ECE2006

Pathogenic mutations in gene RET in patients with medullary thyroid carcinoma found in Polish population

Paszko Z , Sromek M , Czetwertynska M , Czapczak D , Wisniewska A , Skasko E , Kozlowicz-Gudzinska I , Prokurat A , Chrupek M

Aim: The aim of this paper is to summarise the seven’s years of investigations on the frequency and kind of mutations witch occurred in gene RET in patients with medullary thyroid cancer.Methods: Within 330 subjects studied, there were 235 patients with RRT and 95 their healthy relatives. DNA was isolated from peripheral blood lymphocytes. The following exons of the gene RET were amplified by the PCR method: 10, 11, 13, 14, 15 and 16 a...