Endocrine Abstracts

Background: The fetal insulin hypothesis proposes that low birth weight, insulin resistance, and decreased insulin secretion in adulthood are genetically mediated. Babies with low birth weight have higher morbidity and mortality risk in adulthood. However, this situation could also occur in children with adequate weight at birth with genetic risk factors. The polymorphisms rs11708067 in ADCY5 and rs7754840 in CDKAL1 have been associated with low birth weight,...