Searchable abstracts of presentations at key conferences in endocrinology

ea0050ep082 | Neuroendocrinology and Pituitary | SFEBES2017

Ipilimumab induced hypophsitis. A new cause for a rare disease

Shagali Hind , Chinnusamy Ravikumar

Ipilimumab is a monoclonal antibody that had been shown significantly to improve survival in cases of metastatic melanoma. It blocks cytotoxic T-lymphocyte antigen 4(CTLA4) resulting in T-cell activation, proliferation and antitumor response. However recently an emerging clinical entities of different endocrinopathies have been reported in patients on ipilimumab. These are mainly related to lymphocytic hypophysistis causing anterior hypop...

ea0050ep082 | Neuroendocrinology and Pituitary | SFEBES2017

Ipilimumab induced hypophsitis. A new cause for a rare disease

Shagali Hind , Chinnusamy Ravikumar

Ipilimumab is a monoclonal antibody that had been shown significantly to improve survival in cases of metastatic melanoma. It blocks cytotoxic T-lymphocyte antigen 4(CTLA4) resulting in T-cell activation, proliferation and antitumor response. However recently an emerging clinical entities of different endocrinopathies have been reported in patients on ipilimumab. These are mainly related to lymphocytic hypophysistis causing anterior hypop...

ea0044ep66 | (1) | SFEBES2016

Vanishing insulin requirements in patient with type 1 diabetes

Nagi Dinesh , Bachuwar Ravikumar

We describe a case of 31 year young lady with Type 1 Diabetes, who started experiencing reduction in insulin requirement and hypoglycaemia episodes due to an endocrine disorder following Pregnancy. She presented with recurrent episodes of documented hypoglycaemia and amenorrhea following successful pregnancy. Her basal insulin requirements fell from 36 units to 24 units per day and she required little if any insulin as bolus (0.5 unit for every 10 gm). She did not breast feed....

ea0025p325 | Thyroid | SFEBES2011

Iodine induced thyrotoxicosis: the danger of over the counter slimming aids

Bachuwar Ravikumar , Freeman Mark

Over recent years, the numbers of commercially available slimming aids have increased dramatically. Whilst the majority of these aids are harmless, their interaction with normal physiology is either not understood or not brought to the attention of the customer. We report the case of a 45-year-old woman who presented with clinical and biochemical thyrotoxicosis (fT4 31.5 pmol/l, fT3 14.3 pmol/l, TSH <0.02 mIU/l). She had elevated TPO antibodies (51 IU...

ea0062p17 | Poster Presentations | EU2019

Self-diagnosis of De la Chapelle syndrome

Ahmad Sajjad , Ravindran Ravikumar , Lansdown Andrew

Case history: A 30 years old male Caucasian had his saliva tested on a self-funded commercial DNA testing to identify his ancestral roots. The markers for Y chromosome were found to be absent and further evaluation revealed him to have 46 XX karyotype.This was consistent with the diagnosis of De la Chapelle syndrome or XX male syndrome. Fluorescence in situ hybridization (FISH) studies confirmed the presence of SRY (sex determining region Y) gene which was responsible...

ea0044p63 | Clinical biochemistry | SFEBES2016

Pheochromocytoma and Paraganglioma audit

Ravindran Ravikumar , Dacruz Thomas , Rees Aled

Aim: To assess whether using urine catecholamines as a second line investigation has affected clinical decision making in patients with suspected pheochromocytoma and paraganglioma.The need for the audit: New society of endocrine guidelines in June 14, have recommended using urine metanephrines as the initial screening test for PPGL. Current practise at University Hospital Wales is to offer urine catecholamines as the second line test to patients with a ...

ea0013p37 | Clinical practice/governance and case reports | SFEBES2007

Shrinking adrenal mass: Case report of an adrenal pseudocyst

Ravikumar Balasubramanian , Lennard Tom , Pearce Simon

A previously fit 39 year old joiner presented in November 2003 with a 6 month history of intermittent right-sided abdominal pain. There was no associated nausea or vomiting. An abdominal ultrasound requested by his general practitioner revealed a single gallbladder calculus and a 10 cm right-sided cystic mass with some echogenic areas, probably of hepatic or adrenal origin. He was normotensive and clinical examination was normal. CT scan of the abdomen confirmed a 9 cm mass ar...

ea0004p8 | Clinical case reports | SFE2002

Transient thyrotoxicosis following total laryngectomy

Ravikumar C , Mukhtar S , Beshyah S

INTRODUCTION: Disturbance in thyroid function following larygectomy usually manifests as hypothyroidism. Hyperthyroidism is not well recognized. We present a case of transient hyperthyroidism caused by laryngectomy. CASE STUDY: A 58-year-old man underwent total laryngectomy for laryngeal carcinoma. The surgery was not complicated. 3days following surgery, the patient was noted to have sinus tachycardia with a rate between 100 and 110. On the 7th postoperative day thyroid funct...

ea0055p12 | Poster Presentations | SFEEU2018

Idiopathic FSH deficiency

Ravindran Ravikumar , Witczak Justyna , Premawardhana Lakdasa , Adlan Mohamed

Case history: A 24-year-old previously healthy male presented to his GP with unilateral “gynaecomastia”, prompting investigations which showed a low FSH of 0.7 (1–12 IU/l). He had normal libido, erectile function, and a normal sense of smell. He had no children. He was subsequently investigated for persistent dysuria but imaging and cystoscopy were entirely normal. He was a non-smoker who took little alcohol and worked as an insurance agent. His past medical his...

ea0055p17 | Poster Presentations | SFEEU2018

Hypercalcaemia in a body builder

Ravindran Ravikumar , Witczak Justyna , Premawardhana Lakdasa , Adaln Mohamed

Case history: A 53-year-old obsessive body builder, presented with severe constipation. He had used growth hormone, anabolic steroids and testosterone at variable doses for over 20 years. He had a protein intake of over 400 g/day over an extended period. He denied osmotic symptoms, joint or muscle pains, and excessive tiredness. Previously, he had benign prostatic hyperplasia and renal stone disease but was not on any prescription medication and took no over the counter ‘...