Endocrine Abstracts

Introduction: Undernutrition is common in haemodialysed diabetic patients. To estimate the nutritional status before and after dialysis, we followed up prospectively initially undialysed uremic diabetic patients.Methods: All 20 patients had initial body composition (Lean Body Mass, LBM, using DEXA) and serum albumin (SA) measurements. Ten patients underwent hemodialysis (HD) after 15 m (mean). They had a similar LBM & SA evaluation 6.5 m after starti...

Introduction: End-Stage Renal Disease is a common cause of undernutrition, with a high risk of morbidity and mortality in dialysis. To improve nutritional status before dialysis, we followed up 35 non-dialysed uremic diabetic patients in a prospective and cooperative study.Methods: We analysed glomerular filtration rate (GFR, using 51Cr-EDTA), glycemic control (HbA1c), and nutritional status: body composition (lean body mass, LBM, by DEXA), serum albumin...

Background: Familial chylomicronaemia syndrome (FCS) is a rare, inherited disorder characterised by impaired clearance of triglyceride (TG)-rich lipoproteins from plasma, leading to severe hypertriglyceridaemia (HTG), which have major effects on both physical and mental health, and a markedly increased risk of acute pancreatitis. A large overlap in the phenotype between FCS and multifactorial chylomicronaemia syndrome (MCS) contributes to the inconsistency in how patients are ...

Introduction: Patients with Parkinson’s disease on pharmacological treatment frequently loose weight but regain weight after subthalamic nucleus deep brain stimulation (SNBS). This is, at least in part, due to an increase in resting energy expenditure (Perlemoine et al., Br J Nutrition 2005; 93). As SNBS electrodes are located close to the hypothalamic centre regulating food intake, we investigated whether ghrelin levels would vary with SNBS and/or L-DOPA tr...