Endocrine Abstracts

GIP-dependent Cushing’s syndrome (CS) is caused by ectopic expression in adrenal cortex of gastric inhibitory peptide (GIP) receptors coupled to steroidogenesis, which leads to postprandial increases of cortisol (food-dependent CS). In a few cases a transient effect of short-acting octreotide on cortisol levels has been shown, but bilateral adrenalectomy is still thought to be a definitive treatment.We report on a case of a 45-year old woman with bi...

Obesity is considered as a state of chronic, systemic low-grade inflammation. Likely causes include infectious factors, leptin, cigarette smoking, low serum HDL-cholesterol and high serum triglycerides. No definitive confirmation on the causative factor is available so far.The aim of the study was to evaluate serum levels of C-reactive protein (hs-CRP, sensitivity 0,085 ng/L), IL-6, IL-10, TNF-α and its soluble type 2 receptor (sTNF-αR-2) in vi...

Background: Pheochromocytomas and catecholamine-secreting paragangliomas (PPGL) are rare catecholamine-producing tumors. Due to the rarity, limited data on prognosis exists and data are mainly from tertiary centers with potential referral bias. Here, we present population-based mortality data over an observation period of 40 years.Materials and methods: We identified a cohort of 198 PPGL patients diagnosed 1 January 1977 to 31 December 2016 in North and ...