Endocrine Abstracts

Urinary N-Acytyl β-D glucoseaminidase EC: 3.2.1.31 is a lysosomal enzyme which is classified in hexosaminidases group. This enzyme is found in different tissues such as, kidney, liver and spleen, but the kidney has maximum level of enzyme.The first step was the standardization of colourimetry and flourimetry of enzyme assay. In colourimerty method para-nitrophenyl N-acetyl β-D-glucosamine is used as substrate and in flourimetry method the subst...

Objective: We aim of the study was to investigate the clinical approach to Graves’ disease (GD) treatment among endocrinologists in Russia.Materials and methods: An online questionnaire survey was conducted among doctors from Sept till Dec 2021. The questions covered the principles of diagnosis, treatment and dynamic observation of adults with GD.Results: 104 endocrinologists participated in the study. 99% of respondents chose...

Advances in molecular genetics revealed various causes for neonatal diabetes (ND) Wider clinical awareness led to recognition of different phenotypes. In areas like the Gulf, it is expected that the incidence of ND to be higher due to the high frequency of consanguinity. The different ethnic background might result in different causes and phenotypes of ND compared to data reported from the west.We report 19 patients from 11 families with ND. All patients...

Introduction: Vitamin D deficiency is a common clinical finding in the general population and hospitalized patients, including patients in the intensive care unit(ICU). Acute kidney injury (AKI) occurs in more than 50% in ICU admitted patients.Objectives: Due to the fact that there are few studies about AKI in COVID-19 patients, we investigated the relationship between vitamin D3 deficiency and the occurrence of AKI in COVID-19 patients.<p class="abs...

Imipenem (IMP) is a carbapenem antibiotic mainly used to treat nosocomial infection diseases. We aimed to evaluate the oxidative stress of therapeutic doses of imipenem (IMP) on the ovary of ‘wistar’ rats. In this respect, female rats were divided into four groups: animals were intraperitoneally treated with physiological serum, 30, 50 and 80 mg/kg of IMP for one week. We found that therapeutic doses of this drug did not significantly affect the levels of ovarian mal...