Endocrine Abstracts

Introduction: Salt in the principal supply of sodium. In normal conditions the average daily salt intake of Iranian adults is 5–15 gr. 4–6 spoonfuls of salt in a day can be lethal, but for soldiers in equatorial regions 50 grams of salt in a day may be needed. In this study the effects of salt on night sleep was addressed.Method: 20 volunteer students were chosen for the study. They had no problem sleeping before the study. They recorded the ti...

Introduction: Thirst and ADH secretion are two principle mechanisms for controlling body fluid osmolarity. Even an excessive load of salt can effectively be handled by these systems. We studied the effect of salt solution consumption on serum sodium level and osmolarity and the action of these two systems.Method: Seven groups each consisting of 6 male rats weighing 200±20 gr. were chosen. Salt solutions (1,3,5, 7 and 9%) were also provided. The rats...

Background: Neuroendocrine neoplasms (NEN) are known to be associated with specific familial syndromes. However, the incidence of pathogenic germline variants (PGVs) in unselected NEN patients is unknown. In this study, we aim to determine the prevalence and clinical utility of PGVs in unselected NEN patients using universal a genetic testing approach.Methods: We undertook a prospective study of germline genetic testing using a > 80 gene next-generat...