Endocrine Abstracts

Numerous number of studies indicate significant role of oxidative stress in the pathogenesis of thyrotoxicosis. The aim of this work was to estimate oxidative metabolism changes in myocardium and effectiveness of olygocrine in the experimental model of thyrotoxicosis.Methods: Thyrotoxicosis was induced in mature white wistar rats by daily administration of L-thyroxine (100 μg/100 g). We have conducted 3 series of experiments studying: (1) effects of...

Background: The cardiovascular complication is the main cause of morbidity and mortality in obese patients. Endothelial dysfunction and atherosclerosis have the goal role in development of these diseases. The aim of our study was to reveal the role of nitric oxide during obesity associated arterial hypertension.Subject and method: 200 obese patients (age 35–55) were investigated. Control group comprised 25 healthy subjects. We calculated BMI, determ...