Searchable abstracts of presentations at key conferences in endocrinology

ea0011s16 | The endocrinology of psychiatric disease | ECE2006

Effects of hypothyroidism on brain metabolism and its associations with neuropsychiatric impairments

Bauer M , Schlagenhauf F , London E , Miller K , Whybrow PC , Rasgon N , van Herle K , van Herle AJ , Phelps ME , Silverman DHS

Background: Hypothyroidism may profoundly alter mental function and influence mood and cognition, but the neural correlates of these impairments and of thyroid hormone treatment are not well understood.Methods: We prospectively studied 24 subjects, 14 previously untreated newly diagnosed hypothyroid patients (age 42±12 yrs; 11 female, 3 men) and 10 euthyroid control subjects (41±12 yrs). All patients underwent comprehensive neuropsychiatric ass...