Searchable abstracts of presentations at key conferences in endocrinology

ea0011p907 | Thyroid | ECE2006

Comparison of cytogenetic damage in patients with differentiated thyroid cancer receiving ablative 131I therapy in the hypothyroid status versus the euthyroid status (rhTSH assisted treatment)

Frigo A , Francia G , Davi MV , Boni G , Traino C , Scilanga L , Bernardi F , Mariani G , Vaiano A , Colato C , Lo Cascio V , Ferdeghini M

The long-term risk of carcinogenic and genetic damage following the treatment with 131I for differentiated thyroid cancer (DTC) is quite low. The hypothyroid status (HS), at the time of 131I administration, decreases the renal clearance of 131I and increases the whole-body, blood and bone marrow irradiation, unlike the euthyroid status (ES). Chromosome aberrations (CA) in peripheral lymphocytes reflect blood cells exposure to irradiation. This ...