Endocrine Abstracts

Aim of the study was to evaluate whether clinical parameters and echographic patterns may be predictive of malignancy in thyroid nodules with a cytological diagnosis of follicular (FOL) and H?rthle cell (HC) neoplasia. The study included 495 patients (388 F: mean age 45±14 yr; 107 M: mean age 46±14 yr) with FOL (n=418) and CH (n=77) nodules, ‘cold’ at scintiscan and undergone to thyroidectomy. Clinical parameters considered were: sex, age, goi...

Aim of the study was to establish the diagnostic value of nuclear atypia thyroid nodules with cytological diagnosis of follicular (FOL) and Hv¨rthle cell (HC) neoplasia. 1039/23.313 fine needle aspiration (FNA) performed in January 2002 June 2005 in the Department of Endocrinology, University of Pisa had cytological diagnosis of FOL e CH. FNA was performed under echo guidance, using 23 gauge needle attached to 10 mL syringe. The material was air-dryed and stained with Pap...

About 10–15% of FNA cytologies are nondiagnostic, because of inadequate material or indeterminate (i.e. follicular neoplasms). Aim of this study was to analyse the practical usefulness of the analysis of BRAF mutations and RET/PTC rearrangements, known to be associated to papillary thyroid carcinoma (PTC), in FNA-material.We analysed 100 thyroid nodules with a nondiagnostic cytology: 75 follicular nodules and 25 cases with inadequate material. Fifte...