Searchable abstracts of presentations at key conferences in endocrinology

ea0011p537 | Endocrine tumours and neoplasia | ECE2006

Somatostatin receptor subtypes 1–5 in pituitary tumors of various etiologies: investigation by immunohistochemistry

Unger N , Serdiuk I , Saeger W , Wiedemeyer H , Van de Nes J , Schulz S , Stolke D , Mann K , Petersenn S

For somatostatin, five receptor subtypes (sst1-5) have been identified that are widely distributed in various endocrine tissues and tumors. Potent somatostatin analogs like octreotide, lanreotide and the new multiligand SOM230 – with different binding properties to the receptor subtypes - have been developed. We examined somatostatin receptor protein expression in 134 pituitary tumors of various etiologies. Immunostaining was performed with specific polyclonal anti...