Endocrine Abstracts

The renin-angiotensin system (RAS) has been implicated in the development of diabetic vascular complications and angiotensin converting enzyme (ACE) has a major role in this system. This study sought to examine the in vivo effect of aqueous extract of garlic (Allium sativum) on the level of ACE activity of serum from streptozotocin (STZ)-diabetic and non-diabetic rats. Serum ACE activity measured by Cushman and Cheung colorimetric assay in the beginning of diabetes indu...

Thyroid Hormones have extensive effects on differentiation, development, and growth of different organs. In this study the effect of the administration of PTU on pregnant and lactating rats on isolated aorta response of their adult offsprings has been investigated. Three groups of female rats were selected. In the first group (fetal group) observation of vaginal plug after mating was considered as the first day of pregnancy, then PTU was added to their drinking water until the...

Background and aims: To compare and contrast the cardiovascular disease (CVD) risk associated with the metabolic syndrome (MetS) and dysglycemia, independent of each other, we evaluated the 6.7-year incidence risk of CVD and coronary heart disease (CHD).Methods and results: In an Iranian population, 4018 subjects ≥40 years with no history of CVD at baseline, were followed up for new CHD and CVD events. Incidence rates and hazard ratio (HR) were est...