Searchable abstracts of presentations at key conferences in endocrinology

ea0011p847 | Thyroid | ECE2006

Inhibin B/inhibin binding protein complex is differentially expressed in normal and nodular human thyroid tissue

Della Guardia M , Franchi A , Nardo S , Santaguida MG , Sibilla R , Centanni M

Inhibins A and B, peptides belonging to TGF-ß superfamily, have an ubiquitous antagonist action on activin signalling. In thyroid gland, TGF-ß1 and activin mainly exert an inhibitory action on growth and function. In human thyroid, beside the presence of activin β subunits and its transductional elements (ActRI/II, SMAD), there is no evidence for α subunit expression, an essential component for inhibin A/B gathering (α-ßA/α-ßB), nor for ...

ea0004p78 | Reproduction | SFE2002

INTERRELATIONSHIP BETWEEN LEPTIN, TSH AND FREE FATTY ACIDS DURING FASTING IN WOMEN WITH POLYCYSTIC OVARY SYNDROME: DIURNAL COSYNOR ANALYSIS

Macut D , Micic D , Cvijovic G , Sumarac M , Kendereski A , Zarkovic M , Bjekic J , Casanueva F

It is supposed a simillar dirnal change of TSH, free fatty acids (FFA) and leptin in humans. Hypothalamic-pituitary-thyroid axis (HPT) is suppressed during food deprivation while there is an elevation of FFA further influencing glucose metabolism. The aim of our study was to investigate whether leptin can act as a metabolic signal linking the adipose tissue metabolism and the HPT. We studied 13 women with polycystic ovary disease-PCOS (mean age: 26.6±1.83 years; BMI: 34...