Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1254 | Thyroid (non-cancer) | ECE2017

Severe hyperthyroidism imposes large amounts of antithyroid compounds

Mazilu Adina , Spiroiu Cristina , Ranetti A E

We present three cases of females with low body weight that needed large amounts of anti-thyroid drugs – 4–5 mg/kg Thiamazole and 50 mg/kg of Propylthiouracil. First patient, aged 32, weight 45 kg, had Graves’s disease evolving for more than five years. She has been proposed surgery and needed 1200 mg/day of Propylthiouracil. She delayed surgery for 2 weeks, then the dosage required for euthyroidism was 1800 mg/day for three weeks. The goitre had 1.2 kg, from ma...

ea0037ep296 | Calcium and Vitamin D metabolism | ECE2015

Giant parathyroid adenoma with severe hypercalcaemia: case report

Spiroiu Cristina , Ranetti Aurelian Emil , Nistor Claudiu

Introduction: Parathyroid adenomas are the main cause of primary hyperparathyroidism. They are usually small – weighing <1 g – and not easy to find – requiring meticulous imaging studies for localisation. Giant adenomas are uncommon; large tumours and high levels of PTH raise the suspicion of parathyroid malignancy.Case presentation: A 68-year-old female presented in our clinic with polydipsia, poliuria, nausea, weight loss, and extrem...

ea0011p475 | Endocrine tumours and neoplasia | ECE2006

Management of thyroid cancer in children

Mazilu A , Ranetti AE , Mihai A , Spiroiu C

The purpose of the study was to assess the peculiarities of diagnostic and treatment of thyroid cancer in children.Material and method: Between 2000–2005 we screened 234 patients age 3–18 years that presented for various complaints suggesting possible thyroid disease (thyroid enlargement, dysphonia, dysphagia, delayed growth). They were submitted to clinical examination, ultrasonography, T4 and TSH test. The solitary nodules and polinodular goi...

ea0011p476 | Endocrine tumours and neoplasia | ECE2006

Diagnosis difficulties in insulinomas

Ranetti AE , Mazilu A , Spiroiu C , Mihai A

We have studied 5 cases of insulinomas presented in our clinic in 2004–2005 with typical signs and symptoms of hypoglycemia correlated with high insulinemia. The medium insulin value in the morning was 57.9 mUI/ml, but we found values ranging from 10–98 mUI/ml for medium and severe hypoglycemia. There was no correlation between severity of hypoglycemia and insulin level, proven by repeated insulin dosages.The purpose of our analysis was to iden...

ea0011p849 | Thyroid | ECE2006

The efficacy of levothyroxine therapy in the nontoxic multinodular goiter

Mihai AM , Ranetti AE , Spiroiu C , Mazilu A , Ranetti C

There is no ideal treatment for the simple goiter. The treatment options in NMG is: surgery, I131, L-thyroxine or continous monitoring without therapy.From 2000–2003 we evaluated 150 patients (120 women and 30 men) having their agings between 20 and 80 years with L-T4 treatment for nontoxic multinodular goiter. Duration of therapy was 3 years. The pacients was evaluated by clinical examination, level of TSH, free-T4,...

ea0014p501 | (1) | ECE2007

Paraneoplastic Cushing’s syndrome presenting as psychosis – case report

Spiroiu Cristina , Ranetti Aurelian Emil , Mihai Ana- Maria , Mazilu Adina , Diaconu Nicolae

We present the case of a 51 years old woman, nonsmoker, without relevant past medical history, who presented with acute psychotic state starting the third day of treatment with prednisone 30 mg indicated for allergy. She had also arterial hypertension and a significant and progressive loss of proximal muscle strength in her legs. The initial evaluation showed hyperglycemia, metabolic alkalosis and severe hypokalemia. Basal plasma cortisol was high (>90 μg/dl) and did ...