Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep693 | Obesity | ECE2017

Visceral vs subcutaneous white adipose depots response to insulin treatments in rats

Markelic Milica , Jankovic Aleksandra , Golic Igor , Aleksic Marija , Stancic Ana , Otasevic Vesna , Masovic Sava , Marin Marija , Korac Bato , Korac Aleksandra

: White adipose tissue (WAT) has an important role in the regulation of metabolic homeostasis. It is well known that two distinct WAT depots in mammals, subcutaneous WAT (sWAT) and visceral WAT (vWAT) display different metabolic roles and it could be presumed that exert different response to various hormones. Numerous studies revealed leading role of insulin in both fat accumulation (lipogenesis) and adipocyte differentiation (adipogenesis) although it is not clear is there a ...

ea0081ep576 | Endocrine-Related Cancer | ECE2022

Panhypopituitarism and diabetes insipidus due to metastatic breast cancer

Cuconu Diana , Stancu Cristina , Badiu Corin

We report the case of a 36 years old female, with personal history of breast cancer, treated with neoadjuvant chemotherapy, breast sectorectomy and then chemotherapy and radiation therapy 2 years ago. She was continuously monitored by her oncologist, disease free for over a year, with recent CT scan that showed no particular lessions suggestive for secondary disease. Meanwhile, she got pregnant and delivered at term a healthy baby. She was admitted 3 months postpartum with int...

ea0090ep690 | Pituitary and Neuroendocrinology | ECE2023

The role of peptide receptor radionuclide therapy in a case series of bronchial and gastroentero-pancreatic neuroendocrine tumors with secondary determinations

Stefania Stanca Oana , Stancu Cristina , Badiu Corin

Introduction: Neuroendocrine tumors (NET) represent a heterogeneous group of tumors with different locations, whose management is based on the pathology, immunohistochemical, genetic and molecular profile.Materials and method: We followed 8 patients with NET between 2014 and 2022 registered at the “C.I. Parhon” National Institute of Endocrinology, Bucharest, who benefited from peptide receptor radionuclide therapy (PRRT). Among them, 75% were m...

ea0070ep501 | Thyroid | ECE2020

Early diagnosis of acromegaly in chronic thyroiditis-case report

Stancu Ana-Maria , Gabriela Marin Alexandra , Beatrice Preda-Ivascu Monalisa , Mihai Daniel , Stancu Cristina , Badiu Corin

Introduction: Acromegaly is characterized by a pituitary adenoma with excess secretion of GH and IGF-1 hormones. More than 90% of the cases are diagnosed as macroadenomas, after 5 to 10 years of clinical manifestation.Case report: We present the case of a 49 years old man with minor thalassemia, hospitalized in endocrinology department for a routine check of chronic autoimmune thyroiditis. A careful anamnesis showed that in the last year the patient was ...

ea0081ep1082 | Thyroid | ECE2022

Lipid profile during block replace treatment in Graves disease

Stancu Ana-Maria , Dobrescu Ruxandra , Semonia Stanescu Laura , Badiu Corin

Introduction: Graves’ disease (GD) is an autoimmune disorder causing hyperthyroidism. Variations of functional profile as well as type and titer of thyroid specific antibodies makes the control often difficult. One treatment option is adding levothyroxine to anti-thyroid drugs (ATDs), so-called block-replace therapy (BRT).Aim: To study the BRT impact on lipid profile, thyroid function tests (TFTs) and TSH receptor antibodies (TRAb). <p class="ab...

ea0063p1105 | Pituitary and Neuroendocrinology 3 | ECE2019

Aggressive corticotroph adenoma

Stancu Cristina , Enculescu Augustina , Caragheorgheopol Andra , Badiu Corin

Aggressive pituitary tumors (APT) causing Cushing’s Disease are very rare, difficult to treat. The majority of Crooke’s corticotropinomas are macroadenomas, exhibiting rapid growth, resistance to conventional treatments, a high recurrence rate. To date, there is no fully effective method of treatment for these tumors. Pituitary carcinomas (PC) are defined by distant metastasis. PC is exceedingly rare, comprising only 0.1–0.2% of all pituitary neoplasms but APT m...

ea0035p297 | Clinical case reports Thyroid/Others | ECE2014

Thyroid squamous cell carcinoma

Lichiardopol Corina , Surlin Valeriu , Ghilusi Mirela , Bondari Simona , Stancu Irina

Introduction: Squamous cell carcinoma (SCC) is a very rare thyroid carcinoma with aggressive behavior and poor prognosis. Diagnostic difficulties reside in differentiating SCC from other thyroid malignancies and also in establishing its primary or secondary nature, which are both important for treatment strategy.Case report: A 62-year-old woman, with unremarkable personal and family history, presented in October 2013 with progressive enlargement of a rig...

ea0073pep13.4 | Presented ePosters 13: Pituitary and Neuroendocrinology | ECE2021

Long term management in aggressive thyrotropinoma

Stanca Oana , Stancu Cristina , Dumitrascu Anda , Badiu Corin

IntroductionThyrotropinoma is a rare pituitary tumor ( <2% of pituitary adenomas) arising from PIT1-lineage cells, which expresses and secrete TSH. In most cases, the etiology is unknown but rare cases have been described to arise in context of MEN 1 syndrome. Diagnosis is often delayed by confusion with primary hyperthyroidism, which determine the tumor to be already large and invasive at the time of diagnosis. GH and prolactin cosecretion is an increas...

ea0050ep065 | Neuroendocrinology and Pituitary | SFEBES2017

A rare case of primary suprasellar meningeal melanocytoma associated with nonfunctional pituitary adenoma

Paveluc Oana Stefania , Dobrescu Ruxandra , Stancu Cristina , Dumitrascu Anda , Pop Doina , Badiu Corin

Introduction: Pituitary adenomas are the most common pituitary tumours, but in 18% of cases we can find other rare tumours like: Rathke’s cleft cyst, craniopharingyomas, chordomas, meningiomas, infiltrative or infectious disease. Meningeal melanocytoma is a benign neoplasm of central nervous system, commonly located in the base of the brain, cerebellopontine angle and the pineal body, difficult to differentiate from a nonfunctional p...

ea0050ep065 | Neuroendocrinology and Pituitary | SFEBES2017

A rare case of primary suprasellar meningeal melanocytoma associated with nonfunctional pituitary adenoma

Paveluc Oana Stefania , Dobrescu Ruxandra , Stancu Cristina , Dumitrascu Anda , Pop Doina , Badiu Corin

Introduction: Pituitary adenomas are the most common pituitary tumours, but in 18% of cases we can find other rare tumours like: Rathke’s cleft cyst, craniopharingyomas, chordomas, meningiomas, infiltrative or infectious disease. Meningeal melanocytoma is a benign neoplasm of central nervous system, commonly located in the base of the brain, cerebellopontine angle and the pineal body, difficult to differentiate from a nonfunctional p...